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MS4A1 Human
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Membrane Spanning 4-Domains A1 Human Recombinant
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PRO-2515
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Catalogue number
PRO-2515
Synonyms
MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7, B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1.
Introduction
MS4A1 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells. The expression begins at the pro-B phase and until maturity the concentration increases in order to allow optimal B-cell immune response, specifically against T-independent antigens. MS4A1 takes part in the microenvironmental interactions of B cells and also in the regulation of B-cell activation and proliferation. MS4A1 also plays a role as a calcium channel in the cell membrane.
MS4A1 是一种在所有 B 细胞表面表达的活化糖基化磷蛋白。 表达从 pro-B 期开始,直到成熟,浓度增加,以实现最佳的 B 细胞免疫反应,特别是针对 T 非依赖性抗原。 MS4A1 参与 B 细胞的微环境相互作用以及 B 细胞活化和增殖的调节。 MS4A1 还在细胞膜中起到钙通道的作用。
Description
MS4A1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 97 amino acids and having a molecular mass of 11.1kDa .
MS4A1 is fused with a 9 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 MS4A1 Human Recombinant 是单条糖基化多肽链,含有 97 个氨基酸,分子量为 11.1kDa。
MS4A1 在 C 末端与 9 个氨基酸的 His 标签融合,并通过专有色谱技术进行纯化。
Source
Sf9, Insect cells.
Physical Appearance
Formulation
MS4A1 protein solution contains Phosphate buffered saline and 10% glycerol.
Stability
Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by -PAGE.
Amino acid sequence
ADPGIVENEW KRTCSRPKSN IVLLSAEEKK EQTIEIKEEV VGLTETSSQP KNEEDIEIIP IQEEEEEETE TNFPEPPQDQ ESSPIENDSS PHHHHHH.