ProSpec,MS4A1 Human,跨膜 4 域 A1 人重组PRO-2515

  • MS4A1 Human

  • Membrane Spanning 4-Domains A1 Human Recombinant
  • PRO-2515

Catalogue number

PRO-2515

Synonyms

MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7, B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1.

Introduction

MS4A1 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells.  The expression begins at the pro-B phase and until maturity the concentration increases in order to allow optimal B-cell immune response, specifically against T-independent antigens. MS4A1 takes part in the microenvironmental interactions of B cells and also in the regulation of B-cell activation and proliferation. MS4A1 also plays a role as a calcium channel in the cell membrane.

MS4A1 是一种在所有 B 细胞表面表达的活化糖基化磷蛋白。 表达从 pro-B 期开始,直到成熟,浓度增加,以实现最佳的 B 细胞免疫反应,特别是针对 T 非依赖性抗原。 MS4A1 参与 B 细胞的微环境相互作用以及 B 细胞活化和增殖的调节。 MS4A1 还在细胞膜中起到钙通道的作用。

Description

MS4A1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 97 amino acids and having a molecular mass of 11.1kDa .
MS4A1 is fused with a 9 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 MS4A1 Human Recombinant 是单条糖基化多肽链,含有 97 个氨基酸,分子量为 11.1kDa。
MS4A1 在 C 末端与 9 个氨基酸的 His 标签融合,并通过专有色谱技术进行纯化。

Source

Sf9, Insect cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

MS4A1 protein solution contains Phosphate buffered saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

ADPGIVENEW KRTCSRPKSN IVLLSAEEKK EQTIEIKEEV VGLTETSSQP KNEEDIEIIP IQEEEEEETE TNFPEPPQDQ ESSPIENDSS PHHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.