CD5 Human, Sf9
CD5 Human Recombinant, Sf9
CD5 Molecule, Lymphocyte Antigen T1/Leu-1, CD5 Antigen , LEU1, T-Cell Surface Glycoprotein CD5, CD5 Antigen, T1.
CD5 is a suitable immunohistochemical marker for T-cells, though not as sensitive as CD3. Approximately 76% of T-cell neoplasms are reported to express CD5, and it is also observed in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. CD5 is commonly lost in cutaneous T-cell lymphoma, and its deficiency can be used as an indicator of malignancy in this condition. CD5’s absence in T cell acute lymphoblastic leukemia, though relatively rare, is linked with a poor prognosis. CD5 serves as a receptor in regulating T-cell proliferation.
CD5 是一种合适的 T 细胞免疫组织化学标记物，但不如 CD3 敏感。 据报道，大约 76% 的 T 细胞肿瘤表达 CD5，并且在慢性淋巴细胞白血病、毛细胞白血病和套细胞淋巴瘤细胞中也观察到。 CD5 通常在皮肤 T 细胞淋巴瘤中丢失，其缺乏可作为这种情况下恶性肿瘤的指标。 CD5 在 T 细胞急性淋巴细胞白血病中的缺失虽然相对罕见，但与预后不良有关。 CD5 作为调节 T 细胞增殖的受体。
CD5 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 359 amino acids and having a molecular mass of 40kDa . CD5 is expressed with a 6 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.
CD5 protein solution contains Phosphate buffered saline and 10% glycerol.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Amino acid sequence
ADPEFRLSWY DPDFQARLTR SNSKCQGQLE VYLKDGWHMV CSQSWGRSSK QWEDPSQASK VCQRLNCGVP LSLGPFLVTY TPQSSIICYG QLGSFSNCSH SRNDMCHSLG LTCLEPQKTT PPTTRPPPTT TPEPTAPPRL QLVAQSGGQH CAGVVEFYSG SLGGTISYEA QDKTQDLENF LCNNLQCGSF LKHLPETEAG RAQDPGEPRE HQPLPIQWKI QNSSCTSLEH CFRKIKPQKS GRVLALLCSG FQPKVQSRLV GGSSICEGTV EVRQGAQWAA LCDSSSARSS LRWEEVCREQ QCGSVNSYRV LDAGDPTSRG LFCPHQKLSQ CHELWERNSY CKKVFVTCQD PNPHHHHHH.
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.