BDP 576/589 tetrazine

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  • BDP 576/589 tetrazine

BDP 576/589 tetrazine

标签:Tetrazine, BDP 576/589
货号 规格 价格 货期
1G4E0 1 mg 110.00$ in stock
2G4E0 5 mg 290.00$ in stock
3G4E0 10 mg 450.00$ in stock
4G4E0 25 mg 690.00$ in stock
5G4E0 50 mg 1270.00$ in stock
6G4E0 100 mg 1990.00$ in stock

Because of its relatively long excited-state lifetime (about 5 nanoseconds), BDP 576/589 dye can be used in various methods based on measuring fluorescence lifetime. Similarly to other dyes of the BDP family, BDP 576/589 has strong hydrophobic properties and is suitable for labeling non-polar and lypophilic biomolecules and their subsequent visualization by fluorescent microscopy, including two-photon microscopy.

This reagent is a tetrazine derivative that can be conjugated with various strained dienophiles such as trans-cyclooctenes and cyclopropenes. This reaction (TCO ligation) is considered to be one of the best bioconjugation reactions because it is very fast and selective in physiological conditions and does not require additional catalyzers, so it is not toxic in vitro and in vivo.

由于其相对较长的激发态寿命(约 5 纳秒),BDP 576/589 染料可用于基于测量荧光寿命的各种方法。 与 BDP 家族的其他染料类似,BDP 576/589 具有很强的疏水性,适用于标记非极性和亲液性生物分子,并随后通过荧光显微镜(包括双光子显微镜)对其进行可视化。

该试剂是一种四嗪衍生物,可与各种应变亲双烯体(例如反式环辛烯和环丙烯)结合。 该反应(TCO 连接)被认为是最好的生物偶联反应之一,因为它在生理条件下非常快速且具有选择性,并且不需要额外的催化剂,因此在体外和体内都没有毒性。

BDP 576/589 tetrazine相关产品

BDP 581/591 tetrazine

BDP 581/591 is a borondipyrromethene dye with tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.

BDP 581/591 是一种带有四嗪基团的硼二吡咯亚甲基染料,用于逆电子需求 Diels-Alder (IEDDA) 连接。

BDP 576/589 NHS ester

BDP 576/589 NHS ester (BODIPY™ 576/589 analog) is a bright hydrophobic dye with emission in the orange spectrum range. It can be used in fluorescence anisotropy assays.

BDP 576/589 NHS 酯(BODIPY™ 576/589 类似物)是一种明亮的疏水染料,在橙色光谱范围内发射。 它可用于荧光各向异性测定。

BDP 576/589 carboxylic acid

Derivative of BDP 576/589 fluorophore (BODIPY™ 576/589 analog) with non-activated free carboxylic acid group.

BDP 576/589 荧光团(BODIPY™ 576/589 类似物)的衍生物,具有未活化的游离羧酸基团。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 501.16
Molecular weight: 529.17
Molecular formula: C26H23N8BF2O
Solubility: good in polar organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 580
ε, L⋅mol−1⋅cm−1: 98000
Emission maximum, nm: 592
Fluorescence quantum yield: 0.13