产品英文名称: BIO （2’Z,3’E）-6-Bromoindirubin-3-oxime
产品中文名称: BIO （2’Z,3’E）-6-Bromoindirubin-3-oxime
BIO 产品英文简述:
BIO （6-bromoindirubin-3′-oxime） is a specific GSK3 kinase inhibitor. Inhibition of GSK3-beta results in activation of the canonical WNT pathway leading to the translocation of beta-catenin to the nucleus.
This chemical compound from StemRD is 98.5% pure （HPLC）. In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.
Purity: Greater than 98.5% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.