Cosmo Bio抗体,Anti Cartilage Oligomeric Matrix Protein (COMP) mAb (Clone 2127F5),CAC-PRPG-CPF-M02

Cosmo Bio抗体,Anti Cartilage Oligomeric Matrix Protein (COMP) mAb (Clone 2127F5),CAC-PRPG-CPF-M02

Application: IP, ELISA, IHC(p), WB

Clonality: Monoclonal

Host: Mouse

Purification: Supernatant

Reactivity: Human

COMP – Cartilage oligomeric matrix protein – belongs to the thrombospondin family of ECM components and is a prominent multidomain glycoprotein of cartilage, accounting for up to 1% of the wet weight of articular tissues and having an approximate Mr of 97 kDa [1-4]. COMP may also be found in tendon, bone (i.e. osteoblasts), ligament, certain smooth muscles and synovium and more recently has been discovered to be a primary constituent of the dermal ECM [5]. In the ECM COMP is present in a pentameric, disulfide-bonded complex of about 550 kDa, often seen associated with the chondrocyte cell surface [3, 5].