Cosmo Bio抗体,Anti Chondroitin Sulfate A mAb (Clone 2H6),CAC-NU-07-001

硫酸软骨素是蛋白质多糖的多糖部分,是细胞外基质的主要组成部分之一。它由重复单元[→4GlcA 1→3GalNAc 1→]组成,通常以GalNAc的C-4和/或C-6硫酸化。在中枢神经系统中,最丰富的糖胺聚糖是富含[GlcA-GalNAc(4S)]的硫酸软骨素(chondroitin sulfate),即硫酸软骨素a。硫酸软骨素多糖参与神经网络的形成、再生和维持。该单克隆抗体有效识别硫酸软骨素A,特别是在发育中的中枢神经系统中出现的糖胺聚糖。

Application: IP, IHC(p), WB, IHC(f), ELISA

Clonality: Monoclonal

Host: Mouse

Purification: Ion-exchange Chromatography

Reactivity: All

Chondroitin sulfate, a polysaccharide moiety of proteoglycans, is one of the major components of the extracellular matrix. It is composed of the repeating unit, [→4GlcA 1→3GalNAc 1→], commonly sulfated at C-4 and/or C-6 of GalNAc. In the central nervous system, the most abundant glycosaminoglycan is chondroitin sulfate rich in [GlcA-GalNAc(4S)], namely chondroitin sulfate A. Chondroitin sulfate polysaccharides are involved in the formation, regeneration, and maintenance of the neural network. This monoclonal antibody effectively recognizes chondroitin sulfate A, especially in glycosaminoglycans occurring in the developing central nervous system.