ProSpec,CD274 Human,CD274 人重组PRO-1103

  • CD274 Human

  • CD274 Human Recombinant
  • PRO-1103

Catalogue number

PRO-1103

Synonyms

CD274 molecule, CD274 antigen, programmed cell death 1 ligand 1, PD-L1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, B7 homolog 1, B7H1.

Introduction

CD274 takes part in the costimulatory signal, vital for T-cell proliferation and creation of IL10 and IFNG, in a PDCD1-independent and an IL2-dependent manner. CD274 collaboration with PDCD1 inhibits cytokine production and T-cell proliferation.
CD274 以不依赖 PDCD1 和依赖 IL2 的方式参与共刺激信号,这对 T 细胞增殖和 IL10 和 IFNG 的产生至关重要。 CD274 与 PDCD1 协作抑制细胞因子产生和 T 细胞增殖。

Description

CD274 Human Recombinant produced in E. coli is a single polypeptide chain containing 245 amino acids and having a molecular mass of 27.9kDa .
CD274 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CD274 Human Recombinant 是单条多肽链,含有 245 个氨基酸,分子量为 27.9kDa。
CD274 在 N 末端与 25 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The CD274 solution contains 20mM Tris-HCl buffer , 1mM DTT and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMFTVTV PKDLYVVEYG SNMTIECKFP VEKQLDLAAL IVYWEMEDKN IIQFVHGEED LKVQHSSYRQ RARLLKDQLS LGNAALQITD VKLQDAGVYR CMISYGGADY KRITVKVNAP YNKINQRILV VDPVTSEHEL TCQAEGYPKA EVIWTSSDHQ VLSGKTTTTN SKREEKLFNV TSTLRINTTT NEIFYCTFRR LDPEENHTAE LVIPELPLAH PPNER.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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