ProSpec CHM-239,BRAK Human, His,BRAK人重组体,CHM-239

BRAK Human, His

BRAK Human Recombinant , His-Tag
CHM-239

Catalogue number

CHM-239

Synonyms

C-X-C motif chemokine 14, Small-inducible cytokine B14, Chemokine BRAK, Bolekine, NJAC, KS1, Kec, BMAC, MIP-2g, SCYB14, CXCL14, BRAK, MGC10687.

Introduction

CXCL14 is involved in immunoregulatory and inflammatory processes. BRAK protein is structurally related to the CXC subfamily of cytokines. CXCL14 displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. CXCL14 is involved in the homeostasis of monocyte-derived macrophages.
CXCL14 参与免疫调节和炎症过程。 BRAK 蛋白在结构上与细胞因子的 CXC 亚家族相关。 CXCL14 对单核细胞显示趋化活性,但对淋巴细胞、树突细胞、中性粒细胞或巨噬细胞没有趋化活性。 CXCL14 参与单核细胞衍生巨噬细胞的稳态。

Description

CXCL14 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids and having a molecular mass of 10.66 kDa.
The Human BRAK contains a 10 a.a. fusion His tag at N-Terminus.
The BRAK is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CXCL14 Human Recombinant 是一种单一的、非糖基化的多肽链,包含 88 个氨基酸,分子量为 10.66 kDa。
Human BRAK 包含一个 10 a.a. 在 N 末端融合 His 标签。
BRAK 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Filtered White lyophilized powder.

Formulation

CXCL14 filtered and lyophilized from a concentrated solution containing 20mM Tris buffer & 20mM NaCl pH-7.5.

Solubility

建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶冻干的 CXCL14,然后可以进一步稀释成其他水溶液。 产品不是无菌的! 在细胞培养中使用之前,请用适当的无菌过滤器过滤产品。

Stability

Lyophilized BRAK although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BRAK should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
冻干的 BRAK 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 重构后,BRAK 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
对于长期储存,建议添加载体蛋白。
请防止冻融循环。

Purity

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

MKHHHHHHAS SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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