ProSpec,IL 8 Rhesus Macaque CHM-004,白细胞介素8恒河猴重组

IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctakin, K60, NAF, LECT, LUCT, 3-10C, LYNAP, SCYB8, TSG-1, AMCF-I, b-ENAP

Interleukin-8 is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies.When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.

白细胞介素 8 是一种由巨噬细胞和其他细胞类型（如上皮细胞）产生的趋化因子。 它也由内皮细胞合成，内皮细胞将 IL-8 储存在它们的储存囊泡 Weibel-Palade 体中。当第一次遇到抗原时，遇到它的原代细胞是吞噬颗粒的巨噬细胞。 在处理后，它们会释放趋化因子以向其他免疫细胞发出信号，使其进入炎症部位。 IL-8 就是这样一种趋化因子。 它作为一种化学信号，在炎症部位吸引中性粒细胞，因此也称为中性粒细胞趋化因子。

IL 8 Rhesus Macaque Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 79 amino acids and having a molecular mass of 9.1kDa.
The IL 8 Rhesus Macaque is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 IL 8 Rhesus Macaque Recombinant 是一种单一的、非糖基化的多肽链，包含 79 个氨基酸，分子量为 9.1kDa。
IL 8 Rhesus Macaque 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

It is recommended to reconstitute the lyophilized IL-8 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized IL-8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-8 should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by -PAGE.

AVLPRSAKEL RCECIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE PWVQRVVEKF VKRAENQNP

Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 50-150ng/ml, corresponding to a Specific Activity of 6,667-20,000IU/mg.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.