ProSpec-TGFB3 Human, HEK

Transforming Growth Factor-beta3, TGFB3, ARVD, FLJ16571, TGF-beta3.

Transforming growth factor betas mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.

TGF-b 3 Human Recombinant produced in HEK cells is a non-glycosylated homodimer, having a total molecular weight of 25kDa.
The TGF-b 3 is purified by proprietary chromatographic techniques.

HEK.

Sterile Filtered White lyophilized powder.

The TGF-b 3 was lyophilized from 1mg/ml in 1xPBS.

It is recommended to reconstitute the lyophilized TGF-b 3 in sterile 4mM HCl containing 0.1% endotoxin-free recombinant HSA.

Lyophilized TGF-b 3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TGF-b 3 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 95% as obsereved by -PAGE.

The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells and is typically 0.1-0.5ng/ml.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.