ProSpec-Acrp30 Mouse, HEK-CYT-435

Acrp30, AdipoQ, GBP-28, APM-1, ACDC.

Adiponectin is an important negative regulator in hematopoiesis and immune systems. It may be involved in ending inflammatory responses through its inhibitory functions. Inhibits endothelial nf-kappa-b signaling through a camp-dependent pathway. Inhibits tnf-alpha- induced expression of endothelial adhesion molecules. Involved in the control of fat metabolism and insulin sensitivity.

脂联素是造血和免疫系统中重要的负调节剂。 它可能通过其抑制功能参与结束炎症反应。 通过依赖营的途径抑制内皮 nf-kappa-b 信号传导。 抑制 TNF-α 诱导的内皮粘附分子的表达。 参与控制脂肪代谢和胰岛素敏感性。

The Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa.

Acrp30 Mouse Recombinant 与总 Mw 为 26kDa 的 FLAG 标签融合。

HEK293 .

Filtered and lyophilized from 0.5 mg/ml in 0.05M PBS buffer,0.075M NaCl, pH7.4.

It is recommended to reconstitute the lyophilized Acrp30 Mouse in sterile 18M-cm H₂O at 0.5mg/ml, which can then be further diluted to other aqueous solutions.

建议在无菌 18M-cm H2O 中以 0.5mg/ml 的浓度重建冻干的 Acrp30 小鼠，然后可以将其进一步稀释成其他水溶液。

Store lyophilized APM-1 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

将冻干的 APM-1 储存在 -20°C。 重组后分装产品以避免重复的冷冻/解冻循环。 重组蛋白可在 4°C 下保存一段时间； 在 4°C 下两周后它没有显示任何变化。

Greater than 98.0% as determined by -PAGE.

EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYMYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN DYKDDDDK.

Full-length adiponectin activates AMP-activated protein kinase in hepatocyte. Adiponectin also activates AMPK in HepG2 human hepatocytes at the concentration of 1.0 µg/ml.  An in vitro gluconeogenesis assay which was performed in primary rat hepatocytes showed the murine adiponectin derived from mammalian cells can inhibit glucose production.

全长脂联素激活肝细胞中的 AMP 活化蛋白激酶。 浓度为 1.0 µg/ml 的脂联素还能激活 HepG2 人肝细胞中的 AMPK。 在原代大鼠肝细胞中进行的体外糖异生测定表明，源自哺乳动物细胞的鼠脂联素可以抑制葡萄糖的产生。

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。