ProSpec-BAFF Human His/CYT-545

BAFF Human, His

B cell Activating Factor Human Recombinant, His Tag
CYT-545
ProSpec-BAFF Human His/CYT-545 5µg
ProSpec-BAFF Human His/CYT-545 20µg
ProSpec-BAFF Human His/CYT-545 1mg

Catalogue number

CYT-545

Synonyms

BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, TNFSF13B, B-cell Activating Factor.

Introduction

Binds to tnfrsf13b/taci and tnfrsf17/bcma. tnfsf13/april binds to the same 2 receptors, together, they form a 2 ligands -2 receptors pathway involved in the stimulation of b- and t-cell function and the regulation of humoral immunity. a third b-cell specific baff-receptor promotes the survival of mature b-cells and the b-cell response.
B Lymphocyte Stimulator functions as a potent B-cell growth factor in costimulation assays.
Administration of BAFF Human recombinant to mice disrupts splenic B-cell and T-cell zones and results in elevated levels of serum immunoglobulin.
绑定到 tnfrsf13b/taci 和 tnfrsf17/bcma。 tnfsf13/april与相同的2个受体结合,共同形成2个配体-2受体通路,参与刺激b细胞和t细胞功能,调节体液免疫。 第三种 b 细胞特异性 baff 受体促进成熟 b 细胞的存活和 b 细胞反应。
B 淋巴细胞刺激剂在共刺激试验中用作有效的 B 细胞生长因子。
给小鼠施用 BAFF Human 重组体会破坏脾 B 细胞和 T 细胞区域,并导致血清免疫球蛋白水平升高。

Description

BLyS Human Recombinant fused to His tag at N-terminus produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids and having a molecular mass of 21 kDa.
The BAFF His tag fusion protein is purified by proprietary chromatographic techniques.
BLyS Human Recombinant 融合了 N 末端的 His 标签,在大肠杆菌中产生,是一条单一的、非糖基化的多肽链,包含 190 个氨基酸,分子量为 21 kDa。
BAFF His 标签融合蛋白通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

Recombinant His Tag BAFF contains 20mM Tris buffer pH-8 and 5mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAV QGPEETVTQDCLQLIADSET PTIQKGSYTF VPWLLSFKRG SALEEKENKI LVKETGYFFI YGQVLYTDKT YAMGHLIQRK KVHVFGDELS LVTLFRCIQN MPETLPNNSC YSAGIAKLEE GDELQLAIPR ENAQISLDGD VTFFGALKLL.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。

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