ProSpec-BMP 7 Human/CYT-333,Bone Morphogenetic Protein-7 Human Recombinant

Osteogenic Protein 1, BMP-7.

The bone morphogenetic proteins are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

骨形态发生蛋白是可诱导异位骨生长的分泌型信号分子家族。 许多 BMP 是转化生长因子-β 超家族的一部分。 BMP 最初是通过脱矿质骨提取物在骨骼外部位诱导体内软骨内成骨的能力来鉴定的。 基于其在胚胎发生早期的表达，由该基因编码的 BMP 在早期发育中具有拟议的作用。 此外，这种 BMP 与 BMP5 和 BMP7 密切相关的事实已导致推测可能的骨诱导活性。

Bone Morphogenetic Protein-7 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 139 amino acids and having a molecular mass of 15679.97 Dalton.
The BMP-7 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 Bone Morphogenetic Protein-7 Human Recombinant 是一种单体的、非糖基化的多肽链，含有 139 个氨基酸，分子量为 15679.97 道尔顿。
BMP-7 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

BMP-7 was lyophilized from a concentrated sterile solution containing 10mM sodium citrate pH=3.5.

It is recommended to briefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in 20mM-100mM acetic acid at a concentration of 0.1-0.5mg per ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.

建议在打开前对小瓶进行短暂离心，以将内容物带到底部。 在 20mM-100mM 乙酸中复溶，浓度为 0.1-0.5mg/ml。 储备溶液应分配到工作等分试样中并储存在 <-20°C。 应在适当的缓冲溶液中进行进一步稀释。

Lyophilized BMP-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP 7 Human should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 BMP-7 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重组后 BMP 7 Human 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Thr-Gly-Ser-Lys.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。