BMP6 Human
Bone Morphogenetic protein-6 Human Recombinant
CYT-754
2µg
10µg
100µg
Catalogue number
CYT-754
Synonyms
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1, BMP6, VGR, VGR1.
Introduction
The bone morphogenetic proteins are a family of secreted signaling molecules, which can induce ectopic bone growth. Various BMPs are part of the transforming growth factor-beta superfamily. BMPs were initially identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based upon its expression early in embryogenesis, BMP6 has a suggested role in early development. Moreover, the fact that the BMP6 is closely related to BMP5 and BMP7 leads to an assumption of possible bone inductive activity.
骨形态发生蛋白是一个分泌信号分子家族，可诱导异位骨生长。 各种 BMP 是转化生长因子-β 超家族的一部分。 BMP 最初是通过脱矿质骨提取物在骨骼外部位诱导体内软骨内成骨的能力来鉴定的。 基于其在胚胎发生早期的表达，BMP6 在早期发育中具有建议的作用。 此外，BMP6 与 BMP5 和 BMP7 密切相关的事实导致了可能的骨诱导活性的假设。
Description
BMP6 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 164 amino acids and having a molecular mass of 18kDa.
BMP6 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
BMP6 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 BMP6 Human Recombinant 是一条单一的、非糖基化的多肽链，包含 164 个氨基酸，分子量为 18kDa。
BMP6 在 N 端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
BMP6 在 N 端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
The BMP6 solution contains 10mM Sodium citrate buffer and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSASSR RRQQSRNRST QSQDVARVSS ASDYNSSELK TACRKHELYV SFQDLGWQDW IIAPKGYAAN YCDGECSFPL NAHMNATNHA IVQTLVHLMN PEYVPKPCCA PTKLNAISVL YFDDNSNVIL KKYRNMVVRA CGCH.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。