BMPR1B Human
Bone Morphogenetic protein Receptor-1B Human Recombinant
CYT-897
ProSpec-BMPR1B Human/CYT-897 2µg
ProSpec-BMPR1B Human/CYT-897 10µg
ProSpec-BMPR1B Human/CYT-897 100µg
Catalogue number
CYT-897
Synonyms
Bone Morphogenetic Protein Receptor, Type IB, BMP Type-1B Receptor, EC 2.7.11.30, BMPR-1B, ALK6, Bone Morphogenetic Protein Receptor Type-1B, Serine/Threonine Receptor Kinase, CDw293 Antigen, EC 2.7.11, CDw293, ALK-6, Bone morphogenetic protein receptor type-1B.
骨形态发生蛋白受体，IB 型，BMP 1B 型受体，EC 2.7.11.30，BMPR-1B，ALK6，骨形态发生蛋白受体 1B 型，丝氨酸/苏氨酸受体激酶，CDw293 抗原，EC 2.7.11，CDw293，ALK -6，骨形态发生蛋白受体 1B 型。
Introduction
Bone Morphogenetic protein Receptor-1B, also known as BMPR1B belongs to the TKL Ser/Thr protein kinase family. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate as well as activate type I receptors which autophosphorylate, afterward bind and activate SMAD transcriptional regulators. BMPR1B is receptor for BMP7/OP-1 as well as GDF5.
骨形态发生蛋白 Receptor-1B，也称为 BMPR1B，属于 TKL Ser/Thr 蛋白激酶家族。 BMPR1B 与配体结合，形成由两种 II 型和两种 I 型跨膜丝氨酸/苏氨酸激酶组成的受体复合物。 II 型受体磷酸化并激活 I 型受体，I 型受体自身磷酸化，然后结合并激活 SMAD 转录调节因子。 BMPR1B 是 BMP7/OP-1 和 GDF5 的受体。
Description
BMPR1B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 136 amino acids and having a molecular mass of 15.1kDa.
BMPR1B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 BMPR1B Human Recombinant 是一条单一的、非糖基化的多肽链，含有 136 个氨基酸，分子量为 15.1kDa。
BMPR1B 在 N 端与 23 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
BMPR1B protein solution containing Phosphate buffered saline , 20% glycerol, 1mM DTT and 0.1mM PMSF.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 80.0% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSKKEDGES TAPTPRPKVL RCKCHHHCPE DSVNNICSTD GYCFTMIEED DSGLPVVTSG CLGLEGSDFQ CRDTPIPHQR RSIECCTERN ECNKDLHPTL PPLKNRDFVD GPIHHR.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。
