ProSpec-GDF10 Human/CYT-659,Growth differentiation factor 10 Human Recombinant

Bone morphogenetic protein 3b, BMP-3b, Growth/differentiation factor 10, GDF-10, Bone-inducing protein, BIP, GDF10, BMP3B.

GDF10 is a member of the BMP family and the TGF-beta superfamily. GDF10 is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis, and has a role in head formation and possibly multiple roles in skeletal morphogenesis. In humans, GDF10 mRNA is found in the cochlea and lung of fetuses, and in testis, retina, pineal gland, and other neural tissues of adults. The BMP family members are regulators of cell growth and differentiation in both embryonic and adult tissues. These proteins are characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing 7 conserved cysteine residues.

GDF10 是 BMP 家族和 TGF-β 超家族的成员。 GDF10 在股骨、脑、肺、骨骼、肌肉、胰腺和睾丸中表达，并在头部形成中发挥作用，并可能在骨骼形态发生中发挥多种作用。 在人类中，GDF10 mRNA 存在于胎儿的耳蜗和肺中，以及成人的睾丸、视网膜、松果体和其他神经组织中。 BMP 家族成员是胚胎和成人组织中细胞生长和分化的调节剂。 这些蛋白质的特征在于多元蛋白水解加工位点，该位点被切割以产生含有7个保守半胱氨酸残基的成熟蛋白。

GDF10 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 111 amino acids and having a total molecular mass of 12.5 kDa.
GDF10 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 GDF10 Human Recombinant 是一条单一的、非糖基化的多肽链，包含 111 个氨基酸，总分子量为 12.5 kDa。
GDF10 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered colorless solution.

The GDF10 solution contains 10mM Sodium citrate , 1mM DTT, 40% glycerol and 0.1M NaCl.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 95.0% as determined by -PAGE.

MQWDEPRVCS RRYLKVDFAD IGWNEWIISP KSFDAYYCAG ACEFPMPKIV RPSNHATIQS IVRAVGIIPG IPEPCCVPDK MNSLGVLFLD ENRNVVLKVY PNMSVDTCAC R.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。