ProSpec-NT-proBNP Human/CYT-1118

NT-proBNP Human

NT-Pro-B-type Natriuretic Protein Human Recombinant
CYT-1118
ProSpec-NT-proBNP Human/CYT-1118 10µg
ProSpec-NT-proBNP Human/CYT-1118 50µg
ProSpec-NT-proBNP Human/CYT-1118 1mg

Catalogue number

CYT-1118

Synonyms

NPPB, Natriuretic Peptide Precursor B, BNP, B-type Natriuretic Peptide.

Introduction

Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis,vasorelaxation,diuresis and inhibition of renin and aldosterone secretion. BNP plays a key role in cardiovascular homeostasis. BNP also helps restore the body’s salt and water balance andimproves heart function.

利钠肽前体 B 作为一种心脏激素,具有多种生物作用,包括利钠、血管舒张、利尿以及抑制肾素和醛固酮的分泌。 BNP 在心血管稳态中起关键作用。 BNP 还有助于恢复身体的盐和水平衡并改善心脏功能。

Description

NT-Pro-B-type Natriuretic Protein Human Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 76 amino acid and having a molecular mass of approximately 8.5kDa.

NT-proBNP is purified by proprietary chromatographic techniques.

NT-Pro-B-type Natriuretic Protein Human Recombinant 在大肠杆菌中产生,是一种非糖基化多肽链,含有 76 个氨基酸,分子量约为 8.5kDa。

NT-proBNP 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0 and 150mM NaCl.

从 20mM Tris-HCl、pH 8.0 和 150mM NaCl 中的 0.2μm 过滤浓缩溶液冻干。

Solubility

It is recommended to reconstitute the lyophilized NT-Pro-B-type Natriuretic Protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议将冻干的 NT-Pro-B 型利钠蛋白在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶,然后可以进一步稀释成其他水溶液。

Stability

Lyophilized NT-proBNP although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NT-Pro-B-type Natriuretic Protein should be stored at 4°C between 2-7 days and for future use below -18°C.

冻干的 NT-proBNP 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 重构后,NT-Pro-B 型利尿钠蛋白应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。

Please prevent freeze-thaw cycles.

Purity

Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

HPLGSPGSAS DLETSGLQEQ RNHLQGKLSE LQVEQTSLEP LQESPRPTGV WKSREVATEG IRGHRKMVLY TLRAPR.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。

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