ProSpec-Flt3 Ligand Mouse/CYT-340

Flt3 Ligand Mouse

Flt3 Ligand Mouse Recombinant
CYT-340
ProSpec-Flt3 Ligand Mouse/CYT-340 2µg
ProSpec-Flt3 Ligand Mouse/CYT-340 10µg
ProSpec-Flt3 Ligand Mouse/CYT-340 1mg

Catalogue number

CYT-340

Synonyms

Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.

Introduction

FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
FLT3 配体是 fl 细胞因子的受体,具有酪氨酸蛋白激酶活性和调节早期造血细胞增殖的生长因子。 Flt3-配体与其他脑脊液和白细胞介素协同作用以诱导生长和分化。

Description

Flt3-Ligand Mouse Recombinant produced in E.Coli is a non-glycosylated, polypeptide chain containing 163 amino acids and having a molecular mass of 18.6kDa. Flt3-Ligand is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 Flt3-Ligand Mouse Recombinant 是一种非糖基化的多肽链,含有 163 个氨基酸,分子量为 18.6kDa。 Flt3-Ligand 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

The FLT3L Mouse protein was lyophilized from sterile filtered solution containing 10mM sodium phosphate, pH 7.5.

Solubility

It is recommended to reconstitute the lyophilized Flt3l Mouse recombinant in sterile 18MΩ-cm H2O at a concentration of 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Flt-3 Ligand should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.

冻干的 Flt3-Ligand 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,Flt-3 配体应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。 对于长期储存,建议添加载体蛋白。 请防止冻融循环。

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ.

Biological Activity

The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is 4.96ng/ml, corresponding to a specific activity of 2.0×105 units/mg.

通过小鼠 AML5 细胞的剂量依赖性增殖计算的 ED50 为 4.96ng/ml,对应于 2.0×105 单位/mg 的比活性。

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。

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