ProSpec-IFN g Human, His/CYT-478

IFN g Human, His

Interferon-Gamma Human Recombinant, His Tag
CYT-478
ProSpec-IFN g Human, His/CYT-478 10µg
ProSpec-IFN g Human, His/CYT-478 50µg
ProSpec-IFN g Human, His/CYT-478 1mg

Catalogue number

CYT-478

Synonyms

Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma.

Introduction

IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.
IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

由特定抗原或有丝分裂原激活的淋巴细胞产生的 IFN-γ。
IFN-γ除具有抗病毒活性外，还具有重要的免疫调节功能，是巨噬细胞的强效激活剂，对转化细胞具有抗增殖作用，并能增强I型干扰素的抗病毒和抗肿瘤作用。

Description

IFN-Gamma Human Recombinant produced in E.Coli is a single, glycosylated polypeptide chain containing 159 amino acids without cysteine residues and having a molecular mass of 18.5kDa . Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.

IFN-Gamma is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 IFN-Gamma Human Recombinant 是一种单一的糖基化多肽链，含有 159 个氨基酸，不含半胱氨酸残基，分子量为 18.5kDa。蛋白水解加工产生 C 末端异质性，蛋白质在 Gly-150、Met-157 或 Gly-161 处交替结束。
IFN-Gamma 在 N 端与 21 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

Interferon-g is supplied in phosphate-buffered Saline .

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。
储存，在 -20°C 下冷冻更长时间。
请避免冻融循环。

Purity

Greater than 90.0% as determined by analysis by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRG.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.