ProSpec-LIF Human, GST/CYT-001

D factor, MLPLI, HILDA, Emfilermin, Leukemia Inhibitory factor, Differentiation-stimulating factor, Melanoma-derived LPL inhibitor.

Leukemia inhibitory factor, is a pleiotropic cytokine which is expressed by numerous cells including activated T lymphocytes, monocytes, mast cells and neuronal cells. LIF takes part in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and is a key player in immune tolerance at the maternal-fetal interface.

白血病抑制因子是一种多效性细胞因子，由许多细胞表达，包括活化的T淋巴细胞、单核细胞、肥大细胞和神经元细胞。 LIF 参与诱导正常和髓性白血病细胞的造血分化、诱导神经元细胞分化、在肾脏发育过程中调节间充质向上皮细胞的转化，并且是母胎界面免疫耐受的关键参与者。

LIF produced in E.Coli is a single, non-glycosylated polypeptide chain containing 415 amino acids and having a molecular mass of 47.2kDa.
LIF is fused to a 236 amino acid His-GST tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 LIF 是一条单一的、非糖基化的多肽链，含有 415 个氨基酸，分子量为 47.2kDa。
LIF 在 N 末端与 236 个氨基酸的 His-GST 标签融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

The LIF GST protein solution is formulated in 20mM Tris-HCl buffer 1mM DTT, 50mM NaCl and 20% glycerol.

MHHHHHHMSP ILGYWKIKGL VQPTRLLLEY LEEKYEEHLY ERDEGDKWRN KKFELGLEFP NLPYYIDGDV KLTQSMAIIR YIADKHNMLG GCPKERAEIS MLEGAVLDIR YGVSRIAYSK DFETLKVDFL SKLPEMLKMF EDRLCHKTYL NGDHVTHPDF MLYDALDVVL YMDPMCLDAF PKLVCFKKRI EAIPQIDKYL KSSKYIAWPL QGWQATFGGG DHPPKSDLVP RGSHMSPLPI TPVNATCAIR HPCHNNLMNQ IRSQLAQLNG SANALFILYY TAQGEPFPNN LDKLCGPNVT DFPPFHANGT EKAKLVELYR IVVYLGTSLG NITRDQKILN PSALSLHSKL NATADILRGL LSNVLCRLCS KYHVGHVDVT YGPDTSGKDV FQKKKLGCQL LGKYKQIIAV LAQAF

Greater than 90% as determined by -PAGE.

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。
储存，在 -20°C 下冷冻更长时间。
请避免冻融循环。

ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.