ProSpec-TSLPR Human/CYT-742,Thymic Stromal Lymphopoietin Receptor Human Recombinant

TSLPR Human
Thymic Stromal Lymphopoietin Receptor Human Recombinant
CYT-742
5µg
20µg
1mg

Catalogue number

CYT-742

Synonyms

CRL2, CRLF2Y, Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR, ILXR.

Introduction

Thymic Stromal Lymphopoietin Receptor is a member of the type I cytokine receptor family. TSLPR alongside the interleukin 7 receptor activate STAT3, STAT5, and JAK2 pathways, which is regulated processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding dissimilar isoforms have been found for this gene. TSLPR is expressed in heart, skeletal muscle, kidney and adult and fetal liver.
胸腺基质淋巴细胞生成素受体是 I 型细胞因子受体家族的成员。 TSLPR 与白细胞介素 7 受体一起激活 STAT3、STAT5 和 JAK2 通路,这是细胞增殖和造血系统发育等调节过程。 已经为该基因发现了两个编码不同同种型的转录变体。 TSLPR 在心脏、骨骼肌、肾脏以及成人和胎儿肝脏中表达。

Description

TSLPR Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids and having a molecular mass of 26.6kDa.
TSLPR is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 TSLPR Human Recombinant 是一条单一的、非糖基化的多肽链,包含 232 个氨基酸,分子量为 26.6kDa。
TSLPR 在 N 末端与 23 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

TSLPR protein solution contains 20mM Tris-HCl buffer, , 0.4M UREA and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。
储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSQGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SK.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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