ProSpec-TACI Human, His/CYT-032,Tumor Necrosis Factor Receptor 13B Human Recombinant, His Tag

TACI Human, His
Tumor Necrosis Factor Receptor 13B Human Recombinant, His Tag
CYT-032
5µg
20µg
1mg

Catalogue number

CYT-032

Synonyms

CD267, CVID, CVID2, TACI, TNFRSF14B, Tumor necrosis factor receptor superfamily, member 13B, Tumor necrosis factor receptor superfamily, member 13B, isoform CRA_a, TNFRSF13B.

Introduction

TNFRSF13B is a transmembrane receptor protein found predominantly on the surface of B cells . TACI was at first discovered owing to its ability to interact with calcium-modulator and cyclophilin ligand . Later on, it was found that TACI plays a key role in humoral immunity by interacting with two members of the TNF family. Also, TACI controls T cell-independent B cell antibody responses, isotype switching, and B cell homeostasis.
TNFRSF13B 是一种跨膜受体蛋白,主要存在于 B 细胞表面。 最初发现 TACI 是因为它能够与钙调节剂和亲环蛋白配体相互作用。 后来发现TACI通过与TNF家族的两个成员相互作用在体液免疫中起关键作用。 此外,TACI 控制不依赖 T 细胞的 B 细胞抗体反应、同种型转换和 B 细胞稳态。

Description

TACI Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 188 amino acids and having a molecular mass of 20.9kDa. The TACI is purified by proprietary chromatographic techniques.
TACI Human Recombinant 在 N 末端融合了 23 个氨基酸的 His 标签,在大肠杆菌中产生,是一个单一的、非糖基化的多肽链,包含 188 个氨基酸,分子量为 20.9kDa。 TACI 通过专有的色谱技术进行纯化。

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The TACI solution contains 20mM Tris-HCl buffer , 10% glycerol and 0.4M Urea.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMSGLGRS RRGGRSRVDQ EERFPQGLWT GVAMRSCPEE QYWDPLLGTC MSCKTICNHQ SQRTCAAFCR SLSCRKEQGK FYDHLLRDCI SCASICGQHP KQCAYFCENK LRSPVNLPPE LRRQRSGEVE NNSDNSGRYQ GLEHRGSEAS PALPGLKLSA DQVALVYS.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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