ProSpec-WNT3A Human/CYT-861

WNT3A Human

Wingless-Type MMTV Integration Site Family, Member 3A Human Recombinant
CYT-861
ProSpec-WNT3A Human/CYT-861 5µg
ProSpec-WNT3A Human/CYT-861 20µg
ProSpec-WNT3A Human/CYT-861 1mg

Catalogue number

CYT-861

Synonyms

Protein Wnt-3a, MGC119418, MGC119419, MGC119420, WNT3A, wingless-type MMTV integration site family member 3A.

Introduction

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins are implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3A is a member of the WNT gene family. WNT3A is a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. The WNT3A gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.
WNT 基因家族由编码分泌信号蛋白的结构相关基因组成。 这些蛋白质与肿瘤发生和几个发育过程有关,包括在胚胎发生过程中调节细胞命运和模式。 WNT3A 是 WNT 基因家族的成员。 WNT3A 是一种蛋白质,其与小鼠 Wnt3A 蛋白具有 96% 的氨基酸同一性,与人类 WNT3 蛋白(另一种 WNT 基因产物)具有 84% 的氨基酸同一性。 WNT3A基因与另一个家族成员WNT14基因聚集在染色体1q42区域。

Description

WNT3A Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 335 amino acids and having a molecular mass of 37.5kDa. The WNT3A Human is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 WNT3A 人重组体是一条单一的、非糖基化的多肽链,含有 335 个氨基酸,分子量为 37.5kDa。 WNT3A Human 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

The WNT3A Human protein solution contains 20mM Tris-HCl buffer and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

MSYPIWWSLA VGPQYSSLGS QPILCASIPG LVPKQLRFCR NYVEIMPSVA EGIKIGIQEC QHQFRGRRWN CTTVHDSLAI FGPVLDKATR ESAFVHAIAS AGVAFAVTRS CAEGTAAICG CSSRHQGSPG KGWKWGGCSE DIEFGGMVSR EFADARENRP DARSAMNRHN NEAGRQAIAS HMHLKCKCHG LSGSCEVKTC WWSQPDFRAI GDFLKDKYDS ASEMVVEKHR ESRGWVETLR PRYTYFKVPT ERDLVYYEAS PNFCEPNPET GSFGTRDRTC NVSSHGIDGC DLLCCGRGHN ARAERRREKC RCVFHWCCYV SCQECTRVYD VHTCK.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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