ProSpec-TAFA2 Human/CYT-118

Family with sequence similarity 19 -like) member A2, Chemokine-like protein TAFA-2, protein FAM19A2.

TAFA-2 is a 11 kDa secreted protein that belongs to the FAM19/TAFA family of chemokine-like proteins. Similar to other FAM19/TAFA family members, mature TAFA-1 contains 10 regularly spaced cysteine residues with the same pattern: CX7CCX13CXCX14CX11CX4CX5CX10C . Human TAFA-2 is 97% aa identical to mouse TAFA-2 and is expressed in the central nervous system , colon, heart, lung, spleen, kidney, and thymus, however its expression in the CNS is 50 to 1000 fold higher than in other tissues. The biological roles of TAFA family members have not yet been determined.

TAFA-2 是一种 11 kDa 的分泌蛋白，属于趋化因子样蛋白的 FAM19/TAFA 家族。 与其他 FAM19/TAFA 家族成员类似，成熟的 TAFA-1 包含 10 个具有相同模式的规则间隔的半胱氨酸残基：CX7CCX13CXCX14CX11CX4CX5CX10C。 人 TAFA-2 与小鼠 TAFA-2 有 97% 的氨基酸相同，并在中枢神经系统、结肠、心脏、肺、脾、肾和胸腺中表达，但其在中枢神经系统中的表达比在中枢神经系统中高 50 至 1000 倍 其他组织。 TAFA 家族成员的生物学作用尚未确定。

TAFA2 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 101 amino acids and having a molecular mass of 11.2kDa.
The TAFA2 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 TAFA2 Human Recombinant 是一种非糖基化的多肽链，含有 101 个氨基酸，分子量为 11.2kDa。
TAFA2 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

The protein was lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH7.4.

It is recommended to reconstitute the lyophilized TAFA2 in sterile 18M-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议将冻干的 TAFA2 溶解在不低于 100µg/ml 的无菌 18M-cm H2O 中，然后可以进一步稀释成其他水溶液。

Lyophilized TAFA2 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution TAFA2 should be stored at 4C between 2-7 days and for future use below -18C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 TAFA2 虽然在室温下可稳定保存 3 周，但应在 -18C 以下干燥储存。 重组后，TAFA2 应在 4C 下储存 2-7 天，以备将来在 -18C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 97.0% as determined by
Analysis by RP-HPLC.
Analysis by -PAGE.

ANHHKAHHVK TGTCEVVALH RCCNKNKIEE RSQTVKCSCF PGQVAGTTRA APSCVDASIV EQKWWCHMQP CLEGEECKVL PDRKGWSCSS GNKVKTTRVT H

Fully biologically active when compared to standard. Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.