Alkyne-PEG3-COOH

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Alkyne-PEG3-COOH

标签:Alkynes,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
1743-1g 1 g 490.00$ in stock
1743-5g 5 g 980.00$ in stock
1743-25g 25 g please inquire in stock
Alkyne-PEG3-COOH is a bifunctional triethyleneglycol derivative bearing a carboxy group, and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAc reaction.

PEGs are hydrophilic linkers that are useful in the synthesis of water soluble conjugates.

Alkyne-PEG3-COOH 是一种带有羧基和炔烃部分的双功能三甘醇衍生物。 前者可以用肽偶联试剂(如 PyBOP)或碳二亚胺(如 EDC)活化,与胺形成稳定的酰胺键。 炔基可以在 CuAAc 反应中与叠氮化物偶联。

PEG是可用于合成水溶性缀合物的亲水性接头。

Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH

Alkyne-PEG3-COOH相关产品

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.

Sulfo-Cy5 是一种用于 Click 化学的水溶性 Cy5 染料炔烃。

Azide-PEG4-Amine

PEG4 amine azide (CAS# 134179-38-7) is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.

PEG4 amine azide (CAS# 134179-38-7) 是一种具有胺和叠氮化物官能团的双功能接头。 它基于四甘醇核心。 PEG4 接头的长度为 1.4 nm。

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

General properties

Appearance: colorless to yellow oil
Molecular weight: 246.26
CAS number: 1415800-32-6
Molecular formula: C11H18O6
IUPAC name: 3,6,9,12-tetraoxapentadecyn-15-oic acid
Solubility: good in most organic solvents and water
Quality control: NMR 1H, GC-MS (95%, as Me ester)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

相关文献:

  1. Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980