TFA-Amino modifier CPG 500

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TFA-Amino modifier CPG 500

标签:Oligonucleotide synthesis,CPG (controlled pore glass) solid supports for oligonucleotide synthesis
货号 规格 价格 货期
11860 100 mg 60.00$ in stock
21860 250 mg 120.00$ in stock
31860 500 mg 230.00$ in stock
41860 1 g 380.00$ in stock
51860 5 g 1450.00$ 21 days
61860 10 g 2465.00$ 21 days

This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3′-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core – a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.

这种高负载、500 Å 可控孔玻璃固体支持物设计用于合成含有多达 50 个具有 3′-氨基的碱基的寡核苷酸。 氨基受到三氟乙酰 (TFA) 保护,在标准去封闭条件下可轻松去除。

该试剂基于羟基脯氨酸核心 – 一种通用的非核苷结构,天然 100% 手性(缩合时不形成异构体),并且对所有寡核苷酸合成和去封闭条件都稳定。

TFA-Amino modifier CPG 500 TFA-Amino modifier CPG 500 TFA-Amino modifier CPG 500 TFA-Amino modifier CPG 500

TFA-Amino modifier CPG 500相关产品

DMS(O)MT aminolink C6

An amidite for the introduction of amino group.


FAM Phosphoramidite, 6-Isomer

Single isomer 6-FAM phosphoramidite for the synthesis of modified oligonucleotides.

用于合成修饰寡核苷酸的单一异构体 6-FAM 亚磷酰胺。

DusQ2 dT phosphoramidite

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC-MS (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50−80
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases


  1. Taskova, M.; Uhd, J.; Miotke, L.; Kubit, M.; Bell, J.; Ji, H.P.; Astakhova, K. Tandem Oligonucleotide Probe Annealing and Elongation To Discriminate Viral Sequence. Analytical Chemistry, 2017, 89(8), 4363–4366. doi: 10.1021/acs.analchem.7b00646