Alkyne CPG modifier 500

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Alkyne CPG modifier 500

标签:Alkynes,Oligonucleotide synthesis,CPG (controlled pore glass) solid supports for oligonucleotide synthesis
货号 规格 价格 货期
12860 100 mg 60.00$ in stock
22860 250 mg 120.00$ in stock
32860 500 mg 230.00$ in stock
42860 1 g 380.00$ in stock
52860 5 g 1450.00$ in stock

High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3′-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.

Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocol for oligonucleotide modification).

This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.

用于合成具有 3′-炔基的寡核苷酸的高负载可控孔玻璃固体支持物。 使用这种固体支持物,可以合成多达 50 个碱基的寡核苷酸。


这种固体支持物与标准的寡核苷酸去封闭条件兼容。 不需要特殊的解块。

Alkyne CPG modifier 500 Alkyne CPG modifier 500 Alkyne CPG modifier 500 Alkyne CPG modifier 500

Alkyne CPG modifier 500相关产品

Pyrene phosphoramidite dU

Pyrene phosphoramidite with pyrene attached to deoxyuridine.


Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.


FAM-dT phosphoramidite

Phosphoramidite for synthesis of oligonucleotides labeled with fluorescein (FAM) in the middle of sequence.

亚磷酰胺用于合成在序列中间用荧光素 (FAM) 标记的寡核苷酸。

General properties

Appearance: off-white beads
Quality control: NMR 1H and HPLC (95%) of bound reagent, loading measurement
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 70−90
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature
Deprotection conditions: identical to protected nucleobases


  1. Petrunina, N.A.; Lebedev, V.V.; Kirillova, Y.G.; Aralov, A..V.; Varizhuk, A.M.; Sardushkin, M.V. DNA Intercalated Motifs with Non-Nucleoside Inserts. Russian Journal of Bioorganic Chemistry, 2021, 47(6), 1341–1344. doi: 10.1134/S1068162021060212
  2. Svetlova, J.; Sardushkin, M.; Kolganova, N.; Timofeev, E. Recognition Interface of the Thrombin Binding Aptamer Requires Antiparallel Topology of the Quadruplex Core. Biomolecules, 2021, 11(9), 1332. doi: 10.3390/biom11091332