DMS(O)MT aminolink C6

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DMS(O)MT aminolink C6

货号 规格 价格 货期
23260 250 mg 90.00$ in stock
43260 1 g 260.00$ in stock
63260 5 g 950.00$ in stock
83260 10 g 1890.00$ 10 days
93260 25 g please inquire 10 days
Aminolink phosphoramidite for oligonucleotide synthesis. DMS(O)MT is a special protective group similar to traditional MMT, but designed as an improved alternative to it. DMS(O)MT aminolink is fully compatible with standard coupling, deblock, and purification protocols. However, DMS(O)MT group is much better suited for DMT-on and cartridge purification of amino-oligonucleotides because of higher stability, and better oligonucleotide recovery. Oligonucleotides containing DMS(O)MT are more stable in solution than MMT analogs.

In case of cartridge purification, DMS(O)MT protection allows for 2-3 fold increase of oligonucleotide yield, making this reagent a unique solution for high-throughput manufacturing of amino-oligonucleotides.

Aminolink 亚磷酰胺用于寡核苷酸合成。 DMS(O)MT 是一种类似于传统 MMT 的特殊保护基团,但设计为它的改进替代品。 DMS(O)MT 氨基连接与标准偶联、解封闭和纯化方案完全兼容。 然而,由于更高的稳定性和更好的寡核苷酸回收率,DMS(O)MT 组更适合于 DMT-on 和氨基寡核苷酸的柱纯化。 含有 DMS(O)MT 的寡核苷酸在溶液中比 MMT 类似物更稳定。
在柱纯化的情况下,DMS(O)MT 保护可使寡核苷酸产量增加 2-3 倍,使该试剂成为高通量生产氨基寡核苷酸的独特解决方案。

DMS(O)MT aminolink C6相关产品

FAM Phosphoramidite, 6-Isomer

Single isomer 6-FAM phosphoramidite for the synthesis of modified oligonucleotides.

用于合成修饰寡核苷酸的单一异构体 6-FAM 亚磷酰胺。

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R6G phosphoramidite, 6-isomer

Phosphoramidite for synthesis of oligonucleotides labeled at the 5′-terminus with rhodamine 6G (R6G). Pure 6-isomer.

亚磷酰胺用于合成在 5′ 末端用罗丹明 6G (R6G) 标记的寡核苷酸。 纯 6 异构体。

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Phosphate CPG 500 solid support

CPG solid support for the synthesis of 3′-phosphorylated oligonucleotides.

用于合成 3′-磷酸化寡核苷酸的 CPG 固体支持物。

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General properties

Appearance: yellowish viscous oil
Molecular weight: 681.86
CAS number: 1173109-53-9
Molecular formula: C37H52N3O5PS
Solubility: soluble in acetonitrile, dichloromethane
Quality control: NMR 1H, 31P, HPLC (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Oligo synthesis details

Diluent: acetonitrile
Coupling conditions: standard coupling, identical to normal nucleobases
Cleavage conditions: ammonia, 2 h at room temperature; if an oligonucleotide with trityl group needs to be evaporated, add small amount of Tris base before it, or trityl group can be lost.
Deprotection conditions: identical to protected nucleobases. Trityl group can be removed by acidic cleavage in either 80% acetic acid, or on C18 cartridge during purification using 2% to 4% trifluoroacetic acid.


  1. Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j