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- DMS(O)MT aminolink C6
DMS(O)MT aminolink C6
| 货号 | 规格 | 价格 | 货期 |
|---|---|---|---|
| 23260 | 250 mg | 90.00$ | in stock |
| 43260 | 1 g | 260.00$ | in stock |
| 63260 | 5 g | 950.00$ | in stock |
| 83260 | 10 g | 1890.00$ | 10 days |
| 93260 | 25 g | please inquire | 10 days |
In case of cartridge purification, DMS(O)MT protection allows for 2-3 fold increase of oligonucleotide yield, making this reagent a unique solution for high-throughput manufacturing of amino-oligonucleotides.
Aminolink 亚磷酰胺用于寡核苷酸合成。 DMS(O)MT 是一种类似于传统 MMT 的特殊保护基团，但设计为它的改进替代品。 DMS(O)MT 氨基连接与标准偶联、解封闭和纯化方案完全兼容。 然而，由于更高的稳定性和更好的寡核苷酸回收率，DMS(O)MT 组更适合于 DMT-on 和氨基寡核苷酸的柱纯化。 含有 DMS(O)MT 的寡核苷酸在溶液中比 MMT 类似物更稳定。
在柱纯化的情况下，DMS(O)MT 保护可使寡核苷酸产量增加 2-3 倍，使该试剂成为高通量生产氨基寡核苷酸的独特解决方案。
DMS(O)MT aminolink C6相关产品
FAM Phosphoramidite, 6-Isomer
Single isomer 6-FAM phosphoramidite for the synthesis of modified oligonucleotides.
用于合成修饰寡核苷酸的单一异构体 6-FAM 亚磷酰胺。
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Phosphoramidite for synthesis of oligonucleotides labeled at the 5′-terminus with rhodamine 6G (R6G). Pure 6-isomer.
亚磷酰胺用于合成在 5′ 末端用罗丹明 6G (R6G) 标记的寡核苷酸。 纯 6 异构体。
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CPG solid support for the synthesis of 3′-phosphorylated oligonucleotides.
用于合成 3′-磷酸化寡核苷酸的 CPG 固体支持物。
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| Appearance: | yellowish viscous oil |
| Molecular weight: | 681.86 |
| CAS number: | 1173109-53-9 |
| Molecular formula: | C37H52N3O5PS |
| Solubility: | soluble in acetonitrile, dichloromethane |
| Quality control: | NMR 1H, 31P, HPLC (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.
储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 |
| MSDS: | Download |
| Product specifications |
Oligo synthesis details
| Diluent: | acetonitrile |
| Coupling conditions: | standard coupling, identical to normal nucleobases |
| Cleavage conditions: | ammonia, 2 h at room temperature; if an oligonucleotide with trityl group needs to be evaporated, add small amount of Tris base before it, or trityl group can be lost. |
| Deprotection conditions: | identical to protected nucleobases. Trityl group can be removed by acidic cleavage in either 80% acetic acid, or on C18 cartridge during purification using 2% to 4% trifluoroacetic acid. |
相关文献：
- Aparin, I.O.; Farzan, V.M.; Veselova, O.A.; Chistov, A.A.; Podkolzin, A.T.; Ustinov, A.V.; Shipulin, G.A.; Formanovsky, A.A.; Korshun, V.A.; Zatsepin, T.S. 1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay. Analyst, 2016, 141, 1331–1338. doi: 10.1039/c5an01767j