FAM DBCO, 6-isomer

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  • FAM DBCO, 6-isomer

FAM DBCO, 6-isomer

标签:FAM (Fluorescein), Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
151F0 1 mg 110.00$ in stock
251F0 5 mg 210.00$ in stock
451F0 25 mg 160.00$ in stock
551F0 50 mg 270.00$ in stock
651F0 100 mg 420.00$ in stock
Fluorescein (FAM) is one of the oldest yet well known fluorescent dyes. This derivative of FAM contains cyclooctyne group (dibenzocyclooctyne, abbreviated as DBCO or ADIBO) for the conjugation with azides via copper-free, strain-promoted azide alkyne cycloaddition (spAAc).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Azides react with DBCO spontaneously upon simple mixing. The reaction does not require any catalysts, and it is very efficient.

Fluorescein can be detected using a variety of different instruments.

荧光素 (FAM) 是最古老但众所周知的荧光染料之一。 FAM 的这种衍生物含有环辛炔基团(二苯并环辛炔,缩写为 DBCO 或 ADIBO),用于通过无铜、应变促进的叠氮化物炔烃环加成 (spAAc) 与叠氮化物结合。

FAM DBCO 可用于标记蛋白质、肽、核酸和其他含有叠氮基的分子。 叠氮化物在简单混合后会与 DBCO 自发反应。 该反应不需要任何催化剂,而且非常有效。


FAM DBCO, 6-isomer相关产品

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料,用于与叠氮化物的无铜点击化学缀合。

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物,用于 FAM(荧光素)488 nm 通道的硼二吡咯亚甲基染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.


General properties

Appearance: orange solid 橙色固体
Molecular weight: 676.71
Molecular formula: C42H32N2O7
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17