Cyanine5.5 alkyne

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  • Cyanine5.5 alkyne

Cyanine5.5 alkyne

标签:Cyanine5.5, Cy5.5,Alkynes, Microscopy
货号 规格 价格 货期
A70B0 1 mg 110.00$ in stock
B70B0 5 mg 210.00$ in stock
C70B0 10 mg 310.00$ in stock
D70B0 25 mg 410.00$ in stock
E70B0 50 mg 695.00$ in stock
F70B0 100 mg 1190.00$ in stock

Far red / near infrared dye alkyne for Click Chemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore which has been widely used for various applications including intact organism imaging. This reagent can be conjugated with azido groups under mild copper catalyzed Click Chemistry conditions.

This reagent is soluble in organic solvents, but mixtures of water with small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules with this far red/NIR dye.

用于点击化学标记的远红/近红外染料炔烃。 Cyanine5.5 是 Cy5.5® 的类似物,Cy5.5® 是一种流行的荧光团,已广泛用于各种应用,包括完整的生物体成像。 该试剂可以在温和的铜催化点击化学条件下与叠氮基结合。

该试剂可溶于有机溶剂,但水与少量 DMSO 的混合物可用于有效结合。 Cy5.5 炔烃也可用于用这种远红/NIR 染料标记小分子。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 alkyne

Cyanine5.5 alkyne相关产品

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.

用于 Click Chemistry 的反应性近红外 (NIR) 染料,含有末端炔基。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cy5.5 DBCO 是一种远红色的水溶性试剂,用于与叠氮化物的无铜反应。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 656.30
CAS number: 1628790-37-3
Molecular formula: C43H46ClN3O
Solubility: good in organic solvents (DMF, DMSO, acetonitrile, DCM, alcohols), practically insoluble in water (5.2 uM, 3.7 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献:

  1. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  2. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  3. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  4. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
Cy® is a trademark of GE Healthcare.