Cyanine7.5 NHS ester

  • Products
  • Reactive dyes
  • Dye NHS esters
  • Cyanine7.5 NHS ester

Cyanine7.5 NHS ester

标签:Cyanine7.5 NHS esters Near infrared (NIR) imaging Protein labeling
货号 规格 价格 货期
16020 1 mg 110.00$ in stock
26020 5 mg 210.00$ in stock
46020 25 mg 410.00$ in stock
56020 50 mg 695.00$ in stock
66020 100 mg 1190.00$ 5 days

Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.

Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.

This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.

Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS.

Cyanine7.5 是一种具有非常长波发射的 NIR 染料。 该产品是该荧光团的胺反应性衍生物。

近红外辐射很容易穿透组织,可用于体内成像应用。

该产品可用于标记各种含胺基的生物分子,如蛋白质和多肽,通过近红外成像追踪它们在体内的分布。

与 Cy7.5® NHS 的母体结构相比,中心聚甲炔部分的刚性增加允许将量子产率提高 20%。

Cyanine7.5 NHS ester Cyanine7.5 NHS ester Cyanine7.5 NHS ester Cyanine7.5 NHS ester

Cy7.5 absorbance and emission spectra

Cyanine7.5 NHS ester

Cyanine7.5 NHS ester相关产品

Cyanine7.5 tetrazine

Cyanine7.5 is a NIR fluorescent dye with absorption and emission spectra similar to ICG (indocyanine green), but possessing a higher fluorescence quantum yield. This derivative is a tetrazine derivative for the TCO ligation reaction.
Cyanine7.5 是一种近红外荧光染料,其吸收和发射光谱类似于 ICG(吲哚菁绿),但具有更高的荧光量子产率。 该衍生物是用于 TCO 连接反应的四嗪衍生物。

Sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
水溶性磺基-Cyanine3 染料四嗪衍生物,用于用反式环辛烯进行 TCO 连接标记。

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.
Cy5.5 未活化的游离酸性花青染料。

General properties

Appearance: green powder
Mass spec M+ increment: 630.4
Molecular weight: 833.76
CAS number: 2708152-94-5
Molecular formula: C49H52N3BF4O4
IUPAC name: 1H-​Benz[e]​indolium, 2-​[2-​[3-​[2-​(1,​3-​dihydro-​1,​1,​3-​trimethyl-​2H-​benz[e]​indol-​2-​ylidene)​ethylidene]​-​1-​cyclohexen-​1-​yl]​ethenyl]​-​3-​[6-​[(2,​5-​dioxo-​1-​pyrrolidinyl)​oxy]​-​6-​oxohexyl]​-​1,​1-​dimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Kumar, A.; Singam, A.; Swaminathan, G.; Killi, N.; Tangudu, N.K.; Jose, J.; Rathna G.V.N.; Kumar, L.D. Combinatorial therapy using RNAi and curcumin nano-architectures regresses tumors in breast and colon cancer models. Nanoscale, 2022, 14(2), 492–505. doi: 10.1039/D1NR04411G
  2. Tamarov, K.; Wang, J.T.W.; Kari, J.; Happonen, E.; Vesavaara, I.; Niemelä, M.; Perämäki, P.; Al-Jamal, K.T.; Xu, W.; Lehto, V.-P. Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption. ACS Applied Materials & Interfaces, 2021, 13(34), 40392–40400. doi: 10.1021/acsami.1c11875
  3. Babity, S.; Polomska, A.K.; Couture, F.; Bonmarin, M.; Fehr, D.; Detmar, M.; Brambilla, D. Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. Journal of Controlled Release, 2020, 327, 350–359. doi: 10.1016/j.jconrel.2020.08.017
  4. Wang, Y.; Li, L.; Ma, Y.; Tang, Y.; Zhao, Y.; Li, Z.; Pu, W.; Huang, B.; Wen, X.; Cao, X.; Chen, J.; Chen, W.; Zhou, Y.; Zhang, J. A Multifunctional Supramolecular Hydrogel for Prevention of Epidural Adhesion after Laminectomy. ACS Nano, 2020, 14(7), 8202–8219. doi: 10.1021/acsnano.0c01658