Cyanine7 NHS ester

  • Products
  • Reactive dyes
  • Dye NHS esters
  • Cyanine7 NHS ester

Cyanine7 NHS ester

标签:Cyanine7 NHS esters Near infrared (NIR) imaging Protein labeling
货号 规格 价格 货期
15020 1 mg 110.00$ Cyanine7 NHS ester in stock
25020 5 mg 210.00$ Cyanine7 NHS ester 5 days
45020 25 mg 410.00$ Cyanine7 NHS ester in stock
55020 50 mg 695.00$ Cyanine7 NHS ester in stock
65020 100 mg 1190.00$ Cyanine7 NHS ester in stock

Amine reactive Cyanine7, near infrared fluorescent dye, an improved analog of Cy7®.

NIR fluorophores can be used to take advantage of near infrared window of biological tissues – increased transparency of tissues in this spectral region allows to carry out in vivo imaging.

This reagent can be utilized to produce Cyanine7-labeled biomolecules for subsequent use in various in vivo research, and drug design related experiments.

The structure of Cyanine7 features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.

胺反应性 Cyanine7,近红外荧光染料,Cy7® 的改进类似物。

NIR 荧光团可用于利用生物组织的近红外窗口 – 在该光谱区域增加组织的透明度允许进行体内成像。

该试剂可用于生产花青7标记的生物分子,用于后续的各种体内研究和药物设计相关实验。

Cyanine7 的结构具有中央聚甲炔链的刚性设计。 与母体结构相比,这种分子增强可以将量子产率提高 20%,从而增加荧光亮度。

This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cyanine7 NHS ester is also available, and recommended for protein NIR labeling.

该试剂需要用于标记的有机助溶剂(请参阅下面的推荐方案部分)。 也可提供水溶性 Cyanine7 NHS 酯,推荐用于蛋白质 NIR 标记。

Cyanine7 NHS ester Cyanine7 NHS ester Cyanine7 NHS ester Cyanine7 NHS ester

Cy7 absorbance and emission spectra

Cyanine7 NHS ester

Cyanine7 NHS ester相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.
AF488 NHS 酯,一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 is a highly hydrophilic near infrared dye for in vivo imaging. This maleimide derivative is useful for the labeling of thiol groups of proteins and peptides.
sulfo-Cyanine7.5 是一种高度亲水的近红外染料,用于体内成像。 这种马来酰亚胺衍生物可用于标记蛋白质和肽的硫醇基团。

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.
用于 NHS 酯标记的干燥高纯度无胺溶剂。

General properties

Appearance: dark green solid
Molecular weight: 733.64
CAS number: 2408482-09-5
Molecular formula: C41H48N3BF4O4
IUPAC name: 1‐{6‐[(2,5‐dioxopyrrolidin‐1‐yl)oxy]‐6‐oxohexyl}‐ 3,3‐dimethyl‐2‐[(E)‐2‐[(3E)‐3‐{2‐[(2E)‐1,3,3‐ trimethyl‐2,3‐dihydro‐1H‐indol‐2‐ ylidene]ethylidene}cyclohex‐1‐en‐1‐yl]ethenyl]‐3H‐ indol‐1‐ium tetrafluoroborate
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

  1. Yu, J.-H.; Steinberg, I.; Davis, R.M.; Malkovskiy, A.V.; Zlitni, A.; Chung, D.T.; Curet, L.D.; D’Souza, A.L.; Jung, K.o.; Chang, E.; Campbell, J.; Frostig, H.; Park, S.-m.; Pratx, G.; Gambhir, S.S. Noninvasive and Highly Multiplexed Five-Color Tumor Imaging of Near-Infrared Resonant Surface-Enhanced Raman Nanoparticles In Vivo. ChemRxiv, preprint. doi: 10.26434/chemrxiv.13232246.v1
  2. Poreba, M.; Groborz, K.; Rut, W.; Pore, M.; Snipas, S.J.; Vizovisek, M.; Turk, B.; Kuhn, P.; Drag, M.; Salvesen, G.S. The Activome: multiplexed probing of activity of proteolytic enzymes using mass cytometry-compatible activity-based probes (TOF-probes). bioRxiv, preprint. doi: 10.1101/775627
  3. Wang, S.; Latallo, M.J.; Zhang, Z.; Huang, B.; Bobrovnikov, D.G.; Dong, D.; Livingston, N.M.; Tjoeng, W.; Hayes, L.R.; Rothstein, J.D.; Ostrow, L.W.; Wu, B.; Sun, S. Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD. Nature Communications, 2021, 12(1), 4908. doi: 10.1038/s41467-021-25082-9
  4. Song, J.W.; Nam, H.S.; Ahn, J.W.; Park, H.-S.; Kang, D.O.; Kim, H.J.; Kim, Y.H.; Han, J.; Choi, J.Y.; Lee, S.-Y.; Kim, S.; Oh, W.-Y.; Yoo, H.; Park, K.; Kim, J.W. Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque. Theranostics, 2021, 11(18), 8874–8893. doi: 10.7150/thno.59759