Catalog numbers beginning with “CAC” are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.
Application: WB, IHC, RIA
Reactivity: Bovine, Mouse, Rat
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals. It was initially isolated from follicular fluid and was identified as a protein fraction that inhibited follicle-stimulating hormone (FSH) secretion from the anterior pituitary, and so was known as FSH-suppressing protein (FSP). Since then its primary function has been determined to be the binding and bioneutralization agent of members of the TGF- β superfamily, with primary focus on activin.
1) Hasegawa Y, Eto Y, Ibuki Y and Sugino H. (1994) Activin as autocrine and paracrine factor in the ovary. Horm Res. 41(Suppl 1):55-62. PMID: 8088695.