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COSMOSIL Speciality Phases for Difficult HPLC Separations

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COSMOSIL Cholester
COSMOSIL Cholester shows enhanced selectivity over traditional C18 phases, but similar hydrophobicity, for the separation of isomers and other closely related compounds Cholesteryl bonded silica phase Strong stereoselectivity for hydrophobic compounds
COSMOSIL πNAP
COSMOSIL πNAP forms strong π–π interactions with unsaturated compounds. It shows improved selectivity for structural isomers with varying degrees of saturation Naphthylethyl bonded silica phase Stronger π-π interactions than Phenyl phases Useful for positional isomers
COSMOSIL PYE
COSMOSIL PYE has the most powerful π-π interactions and is particularly suited for the separation of aromatic isomers Pyrenylethyl bonded silica phase Multiple separation modes – hydrophobic, charge transfer and π-π interactions
COSMOSIL HILIC
COSMOSIL HILIC retains polar analytes that are poorly retained in reversed-phase chromatography Triazole bonded silica phase Retention of acidic analytes by anion-exchange Enhanced sensitivity in LC-MS
COSMOSIL Sugar-D
COSMOSIL Sugar-D shows improved column durability compared to conventional amino bonded phases, for the analysis of saccharides Separation of small saccharides and sugar alcohols Separation of highly hydrophilic compounds

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