- CPG solid supports
- DusQ3 CPG 500
DusQ3 CPG 500
|Cat. #||Quantity||Price||Lead time|
|1618-1g||1 g||990.00$||21 days|
DusQ3 is a dark quencher for far red and near infrared fluorophores, especially suitable for Cyanine5.5.
The dye can be attached to 3′-terminus of oligonucleotides by means of automated solid phase synthesis using this support. The dye is sensitive to nucleophilic reagents, and therefore must be carefully deprotected. We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of the quencher can be used.
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DusQ1 CPG 500
Controlled pore glass (CPG) 500 solid support for synthesis of oligonucleotides with 3’-terminal DusQ1 quencher. Compatible with standard deblocking conditions.
DusQ2 CPG 500
Controlled pore glass (CPG) 500 modified support for the synthesis of oligonucleotides with DusQ2 quencher at the 3’ end. Compatible with standard deblocking conditions.
|Appearance:||dark blue beads|
|Quality control:||1H NMR of bound reagent, coupling testing with HPLC-MS|
|Storage conditions:||24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.|
Oligo synthesis details
|Pore size, Å:||500|
|Typical loading, umol/g:||50-80|
|Coupling conditions:||standard, ultramild phosphoramidites|
|Cleavage conditions:||2 h / rt, 30% aq. ammonia (ultramild protective groups)|