ProSpec,CD200R1 Human,CD200 受体 1 人重组体PRO-2548

  • CD200R1 Human

  • CD200 Receptor 1 Human Recombinant
  • PRO-2548

Catalogue number

PRO-2548

Synonyms

Cell surface glycoprotein CD200 receptor 1 isoform d, CD200R1, CD200R, HCRTR2, MOX2R, OX2R, Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, Cd200r1, Mox2r, Ox2r.

Introduction

CD200R1, also known as cell surface glycoprotein CD200 receptor 1, is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 inhibitory signaling pathway has been involved in taking a prominent role in limiting inflammation in a broad range of inflammatory diseases. CD200R1 signaling inhibits the expression of proinflammatory molecules including tumor necrosis factor, interferons, in addition to inducible nitric oxide synthase in response to selected stimuli.

CD200R1,也称为细胞表面糖蛋白 CD200 受体 1,是一种在髓系细胞上表达的 CD200 受体同种型。 CD200R1 抑制信号通路在广泛的炎症性疾病中在限制炎症方面发挥着重要作用。 CD200R1 信号传导抑制促炎分子的表达,包括肿瘤坏死因子、干扰素,以及响应选定刺激的诱导型一氧化氮合酶。

Description

CD200R1 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 462 amino acids and having a molecular mass of 51.9kDa . CD200R1 is expressed with 242 amino acids His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 昆虫细胞中产生的 CD200R1 是单条糖基化多肽链,含有 462 个氨基酸,分子量为 51.9kDa。 CD200R1 在 C 末端用 242 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD200R1 protein solution contains phosphate buffered saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

ADLSSSLCMD EKQITQNYSK VLAEVNTSWP VKMATNAVLC CPPIALRNLI IITWEIILRG QPSCTKAYKK ETNETKETNC TDERITWVSR PDQNSDLQIR TVAITHDGYY RCIMVTPDGN FHRGYHLQVL VTPEVTLFQN RNRTAVCKAV AGKPAAHISW IPEGDCATKQ EYWSNGTVTV KSTCHWEVHN VSTVTCHVSH LTGNKSLYIE LLPVPGAKKS AKLLEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.

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