Posted on By 上海金畔生物

ProSpec,CD300A Human,CD300A 人重组PRO-1618

  • CD300A Human

  • CD300A Human Recombinant
  • PRO-1618

Catalogue number

PRO-1618

Synonyms

CD300a Molecule, CD300a Antigen, IRp60, CD300 Antigen-Like Family Member A, NK Inhibitory Receptor, Immunoglobulin Superfamily Member 12, CMRF35-Like Molecule 8, CMRF35-H, Inhibitory Receptor Protein 60, CMRF-35-H9, CMRF-35H, CLM-8, IRC1, IRC2, CMRF35H Leukocyte Immunoglobulin-Like Receptor, Leukocyte Membrane Antigen, IgSF12.
CD300a 分子、CD300a 抗原、IRp60、CD300 抗原样家族成员 A、NK 抑制性受体、免疫球蛋白超家族成员 12、CMRF35 样分子 8、CMRF35-H、抑制性受体蛋白 60、CMRF-35-H9、CMRF-35H、 CLM-8、IRC1、IRC2、CMRF35H 白细胞免疫球蛋白样受体、白细胞膜抗原、IgSF12。

Introduction

CD300A belongs to the CD300 family and contains 1 Ig-like V-type domain. The protein is expressed not only by natural killer cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. CD300A is inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer cells, and to the down-regulation of mast cell degranulation.
CD300A 属于 CD300 家族，包含 1 个 Ig 样 V 型结构域。 该蛋白质不仅由自然杀伤细胞表达，而且由 T 细胞亚群、B 细胞、树突细胞、肥大细胞、粒细胞和单核细胞表达。 CD300A 是抑制性受体，可能有助于下调自然杀伤细胞的溶细胞活性，并有助于下调肥大细胞脱粒。

Description

CD300A Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 134 amino acids and having a molecular mass of 14.7kDa.
CD300A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CD300A 人重组体是一条单一的、非糖基化的多肽链，含有 134 个氨基酸，分子量为 14.7kDa。
CD300A 在 N 末端与 23 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

The CD300A solution contains 20mM Tris-HCl buffer , 0.15M NaCl, 1mM DTT and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSLSKCRTV AGPVGGSLSV QCPYEKEHRT LNKYWCRPPQ IFLCDKIVET KGSAGKRNGR VSIRDSPANL SFTVTLENLT EEDAGTYWCG VDTPWLRDFH DPVVEVEVSV FPAS

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.