ProSpec,CD8B Human,CD8B人重组PRO-1843

  • CD8B Human

  • CD8B Human Recombinant
  • PRO-1843

Catalogue number

PRO-1843

Synonyms

T Lymphocyte Surface Glycoprotein Beta Chain, CD8 Antigen, Beta Polypeptide 1 , CD8b Molecule, CD8b Antigen, T-Cell Surface Glycoprotein CD8 Beta Chain, CD8B1, LYT3, LY3, LEU2, P37.

Introduction

CD8B encodes the CD8 beta chain isoforms of the CD8 antigen. CD8 is a cell surface glycoprotein which facilitates efficient cell-cell interactions within the immune system and is located on most cytotoxic T lymphocytes. The T-cell receptor on the T lymphocyte and the co-receptor CD8 antigen identify antigens exposed by an antigen presenting cell in the context of class I MHC molecules. The functional co-receptor is either a heterodimer composed of one alpha and one beta chain or a homodimer composed of two alpha chains. Both alpha and beta chains share substantial homology to immunoglobulin variable light chains.
CD8B 编码 CD8 抗原的 CD8 β 链异构体。 CD8 是一种细胞表面糖蛋白,可促进免疫系统内有效的细胞间相互作用,位于大多数细胞毒性 T 淋巴细胞上。 T 淋巴细胞上的 T 细胞受体和辅助受体 CD8 抗原识别在 I 类 MHC 分子的情况下由抗原呈递细胞暴露的抗原。 功能性共受体是由一条α链和一条β链组成的异二聚体或由两条α链组成的同源二聚体。 α 和 β 链都与免疫球蛋白可变轻链具有实质性的同源性。

Description

CD8B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 172 amino acids and having a molecular mass of 19.2 kDa. CD8B is fused to a 23 amino acid His-tag at N-terminus.
在大肠杆菌中产生的 CD8B Human Recombinant 是一个单一的、非糖基化的多肽链,包含 172 个氨基酸,分子量为 19.2 kDa。 CD8B 在 N 端与 23 个氨基酸的 His 标签融合。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

The CD8B solution contains 20mM Tris-HCl buffer , 0.4M Urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。

Purity

Greater than 80% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SP

Usage

ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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