ProSpec-CD8B Human Sf9,CD8B人重组PRO-2508

  • CD8B Human, Sf9

  • CD8B Human Recombinant, Sf9
  • PRO-2508

Catalogue number

PRO-2508

Synonyms

CD8b Molecule, CD8 Antigen, Beta Polypeptide 1 , CD8B1, T Lymphocyte Surface Glycoprotein Beta Chain, T-Cell Surface Glycoprotein CD8 Beta Chain, CD8b Antigen, Leu2, LYT3, P37, LY3, T-cell surface glycoprotein CD8 beta chain.

Introduction

CD8B encodes the CD8 beta chain isoforms of the CD8 antigen. CD8 is a cell surface glycoprotein which facilitates efficient cell-cell interactions within the immune system and is located on most cytotoxic T lymphocytes. The T-cell receptor on the T lymphocyte and the co-receptor CD8 antigen identify antigens exposed by an antigen presenting cell in the context of class I MHC molecules. The functional co-receptor is either a heterodimer composed of one alpha and one beta chain or a homodimer composed of two alpha chains. Both alpha and beta chains share substantial homology to immunoglobulin variable light chains.

CD8B 编码 CD8 抗原的 CD8 β 链异构体。 CD8 是一种细胞表面糖蛋白,可促进免疫系统内有效的细胞间相互作用,位于大多数细胞毒性 T 淋巴细胞上。 T 淋巴细胞上的 T 细胞受体和辅助受体 CD8 抗原识别在 I 类 MHC 分子的情况下由抗原呈递细胞暴露的抗原。 功能性共受体是由一条α链和一条β链组成的异二聚体或由两条α链组成的同源二聚体。 α 和 β 链都与免疫球蛋白可变轻链具有实质性的同源性。

Description

CD8B produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 158 amino acids and having a molecular mass of 17.8kDa. .
CD8B is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD8B protein solution contains 10% glycerol & Phosphate Buffered Saline .

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 85.0% as determined by -PAGE.

Amino acid sequence

ADPLQQTPAY IKVQTNKMVM LSCEAKISLS NMRIYWLRQR QAPSHHE FLALWDSAKG TIHGEEVEQE KIAVFRDASR FILNLTSVKP EDSGIYFCMI VGSPELTFGK GTQLSVVDFL PTTAQPTKKS TLKKRVCRLP RPETQKGPLC SPHHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

  • CD8B Human