ProSpec,FCGR2B Human,CD32 人重组PRO-1295

CD32, CD32B, FCG2, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma-RIIb, FcRII-b.

FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. FCGR2B participates in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. FCGR2B Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta . Variants in FCGR2B may increase susceptibilty to systemic lupus erythematosus .

FCGR2B 是免疫球蛋白 γ 复合物 Fc 区的低亲和力受体。 FCGR2B 参与免疫复合物的吞噬作用和 B 细胞产生抗体的调节。 FCGR2B 在单核细胞、中性粒细胞、巨噬细胞、嗜碱性粒细胞、嗜酸性粒细胞、朗格汉斯细胞、B 细胞、血小板细胞和胎盘中表达。 FCGR2B 的变异体可能会增加对系统性红斑狼疮的易感性。

FCGR2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 197 amino acids and having a molecular mass of 22.0kDa. FCGR2Bis fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 FCGR2B Human Recombinant 是一条单一的、非糖基化的多肽链，包含 197 个氨基酸，分子量为 22.0kDa。 FCGR2Bis 在 N 末端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

FCGR2B protein solution contains 20mM Tris-HCl buffer , 0.15M NaCl, 30% glycerol and 1mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Greater than 95.0% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSHMAPPKA VLKLEPQWIN VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAP.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.