ProSpec,CD209 Human,CD209 人重组PRO-2722

CD209 antigen, CD209 antigen isoform 1, C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD209, CLEC4L, CDSIGN

CD209 is Pathogen-recognition receptor expressed on the surface of immature dendritic cells andtakes part in initiation of primary immune response.CD209has a high affinity for theICAM3 molecule and binds various microorganisms by recognizing high-mannose-containing glycoproteins ontheir envelopes and especially functions as receptor for several viruses such as HIV and Hepatitis C. Along with other C-typelectins, CD209is involved in recognition of tumors by dendritic cells.CD209also initiatesnatural immunity bymodulating toll-like receptors.

CD209是在未成熟树突状细胞表面表达的病原体识别受体，参与初级免疫反应的启动。CD209对ICAM3分子具有高亲和力，通过识别其包膜上含高甘露糖的糖蛋白与各种微生物结合，特别是作为受体 几种病毒，如 HIV 和丙型肝炎。与其他 C 型凝集素一起，CD209 参与树突状细胞对肿瘤的识别。CD209 还通过调节 toll 样受体启动自然免疫。

CD209 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 587 amino acids and having a molecular mass of 66.5kDa.
CD209 is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.

Sf9, Baculovirus cells.

Sterile filtered colorless solution.

The CD209 solution contains 10% glycerol and Phosphate-Buffered Saline .

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Greater than 90.0% as determined by -PAGE.

ADPVSKVPSS ISQEQSRQDA IYQNLTQLKA AVGELSEKSK LQEIYQELTQ LKAAVGELPE KSKLQEIYQE LTRLKAAVGE LPEKSKLQEI YQELTWLKAA VGELPEKSKM QEIYQELTRL KAAVGELPEK SKQQEIYQEL TRLKAAVGEL PEKSKQQEIY QELTRLKAAV GELPEKSKQQ EIYQELTQLK AAVERLCHPC PWEWTFFQGN CYFMSNSQRN WHDSITACKE VGAQLVVIKS AEEQNFLQLQ SSRSNRFTWM GLSDLNQEGT WQWVDGSPLL PSFKQYWNRG EPNNVGEEDC AEFSGNGWND DKCNLAKFWI CKKSAASCSR DEEQFLSPAP ATPNPPPAVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.