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ProSpec,CD38 Human,CD38 人重组PRO-2320

  • CD38 Human

  • CD38 Human Recombinant
  • PRO-2320

Catalogue number

PRO-2320

Synonyms

P28907, ADP-Ribosyl Cyclase 1, 2-Phospho-Cyclic-ADP-Ribose Transferase, Cyclic ADP-Ribose Hydrolase, 2-Phospho-ADP-Ribosyl Cyclase, NAD Nucleosidase, CD38 Antigen , ADPRC 1, 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase, Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase , Cluster Of Differentiation 38, CADPr Hydrolase 1,CD38 Antigen, EC 2.4.99.20, EC 3.2.2.6, ADPRC1, T10.

Introduction

CD38 is a surface molecule which acts as a plasma membrane signaling receptor in leukocytes. Furthermore, CD38 functions as signaling channel which leads to to cellular activation and proliferation. CD38 also plays a role as an ectoenzyme with various functions as well as an inducer of Ca2+ mobilization from cytoplasmic stores. CD38 signals acts as a coreceptor on B cells and modulates B cell receptor.
CD38 是一种表面分子，在白细胞中充当质膜信号受体。 此外，CD38 作为信号通道发挥作用，导致细胞活化和增殖。 CD38 还作为具有各种功能的胞外酶以及从细胞质储存中调动 Ca2+ 的诱导剂发挥作用。 CD38 信号作为 B 细胞的辅助受体并调节 B 细胞受体。

Description

CD38 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 269 amino acids and having a molecular mass of 31.2kDa .
CD38 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 CD38 是单条糖基化多肽链，包含 269 个氨基酸，分子量为 31.2kDa。
CD38 在 C 末端用 6 个氨基酸的 His 标签表达，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD38 protein solution contains 50mM MES buffer , 100mM NaCl and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.

For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

ADPEFVPRWR QQWSGPGTTK RFPETVLARC VKYTEIHPEM RHVDCQSVWD AFKGAFISKH PCNITEEDYQ PLMKLGTQTV PCNKILLWSR IKDLAHQFTQ VQRDMFTLED TLLGYLADDL TWCGEFNTSK INYQSCPDWR KDCSNNPVSV FWKTVSRRFA EAACDVVHVM LNGSRSKIFD KNSTFGSVEV HNLQPEKVQT LEAWVIHGGR EDSRDLCQDP TIKELESIIS KRNIQFSCKN IYRPDKFLQC VKNPEDSSCT SEIHHHHHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.