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CD43 Human
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CD43 Human Recombinant
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PRO-1687
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Catalogue number
PRO-1687
Synonyms
Leukosialin, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, SPN, CD43, leukosialin precursor, GPL115, LSN.
Introduction
CD43 is a key sialoglycoprotein located in the surface of T lymphocytes, monocytes, granulocytes, thymocytes and some B lymphocytes. CD43 is a part of a physiologic ligand-receptor complex which participates in T-cell activation. Throughout T-cell activation, CD43 is actively taken out from the T-cell-APC contact site, signifying CD43 has a negative regulatory role in adaptive immune response.
CD43是位于T淋巴细胞、单核细胞、粒细胞、胸腺细胞和一些B淋巴细胞表面的关键唾液酸糖蛋白。 CD43 是参与 T 细胞活化的生理配体-受体复合物的一部分。 在整个 T 细胞激活过程中，CD43 被主动从 T 细胞-APC 接触部位取出，表明 CD43 在适应性免疫反应中具有负调节作用。
Description
CD43 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 257 amino acids and having a molecular mass of 25.8kDa.
CD43 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
CD43 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 CD43 Human Recombinant 是一条单一的、非糖基化的多肽链，包含 257 个氨基酸，分子量为 25.8kDa。
CD43 在 N 末端与 23 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。
CD43 在 N 末端与 23 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
CD43 protein solution containing 20mM Tris-HCl buffer , 0.15M NaCl and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSSTTAVQT PTSGEPLVST SEPLSSKMYT TSITSDPKAD STGDQTSALP PSTSINEGSP LWTSIGASTG SPLPEPTTYQ EVSIKMSSVP QETPHATSHP AVPITANSLG SHTVTGGTIT TNSPETSSRT SGAPVTTAAS SLETSRGTSG PPLTMATVSL ETSKGTSGPP VTMATDSLET STGTTGPPVT MTTGSLEPSS GASGPQVSSV KLSTMMSPTT STNASTVPFR NPDENSR.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.