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CD69 Human
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CD69 Human Recombinant
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PRO-2262
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Catalogue number
PRO-2262
Synonyms
CD69 Molecule, CD69 Antigen , Early T-Cell Activation Antigen P60, Leukocyte Surface Antigen Leu-23, BL-AC/P26, GP32/28, CLEC2C, MLR-3, AIM, EA1, C-Type Lectin Domain Family 2, Member C, Activation Inducer Molecule , C-Type Lectin Domain Family 2 Member C, Early Lymphocyte Activation Antigen, Activation Inducer Molecule, CD69 Antigen, Early activation antigen CD69.
Introduction
CD69 is a type 2 transmembrane glycoprotein which belongs to the C-type lectin family. CD69 is a very early activation Ag of T lymphocytes. The expression of CD69 is induced upon activation of T lymphocytes, and CD69 takes part in proliferation. Moreover, CD69 acts to transmit signals in natural killer cells as well as platelets. CD69 functions in the pathogenesis of allergen induced eosinophilic airway inflammation and responsiveness. Among the diseases which are associated with CD69: cd3gamma deficiency and mast cell disease.
CD69是属于C型凝集素家族的2型跨膜糖蛋白。 CD69 是一种非常早期的 T 淋巴细胞活化抗原。 T淋巴细胞活化后诱导CD69表达，CD69参与增殖。 此外，CD69 在自然杀伤细胞和血小板中起到传递信号的作用。 CD69 在过敏原诱导的嗜酸性气道炎症和反应性的发病机制中起作用。 在与 CD69 相关的疾病中：cd3gamma 缺乏症和肥大细胞病。
Description
CD69 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 147 amino acids and having a molecular mass of 17.0kDa.
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CD69 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile Filtered clear solution.
Formulation
CD69 protein solution contains Phosphate Buffered Saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
ADPSVGQYNC PGQYTFSMPS DSHVSSCSED WVGYQRKCYF ISTVKRSWTS AQNACSEHGA TLAVIDSEKD MNFLKRYAGR EEHWVGLKKE PGHPWKWSNG KEFNNWFNVT GSDKCVFLKN TEVSSMECEK NLYWICNKPY KHHHHHH.
Usage
Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.