ProSpec,CD81 Human,CD81人重组PRO-2472

  • CD81 Human

  • CD81 Human Recombinant
  • PRO-2472

Catalogue number

PRO-2472

Synonyms

CD81 Molecule, CD81 Antigen , 26 KDa Cell Surface Protein TAPA-1, Tetraspanin-28, CD81 Antigen, Tspan-28, TSPAN28, TAPA1, Target Of The Antiproliferative Antibody 1, CVID6, S5.7, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28.

Introduction

CD81 antigen isoform 1, also known as CD81, is part of the tetraspanin family. CD81 interacts directly with immunoglobulin superfamily member 8 and CD36. In B cells, CD81 is part of a complex with CD21, CD19 and Leu13. Furthermore, this complex decreases the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. While on T cells CD81 connects with CD4 and CD8 and provides a costimulatory signal with CD3.

CD81 抗原异构体 1,也称为 CD81,是四跨膜蛋白家族的一部分。 CD81 直接与免疫球蛋白超家族成员 8 和 CD36 相互作用。 在 B 细胞中,CD81 是 CD21、CD19 和 Leu13 复合物的一部分。 此外,该复合物通过连接 Ag 特异性识别和 CD21 介体识别,降低了 B 细胞受体激活 B 细胞的阈值。 而在 T 细胞上,CD81 与 CD4 和 CD8 连接,并提供与 CD3 的共刺激信号。

Description

CD81 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 331 amino acids and having a molecular mass of 37.0kDa. .
CD81 is expressed with a 242 amino acid hIgG-His-tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 CD81 是单条糖基化多肽链,含有 331 个氨基酸,分子量为 37.0kDa。 .
CD81 在 C 末端用 242 个氨基酸的 hIgG-His-tag 表达,并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CD81 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Amino acid sequence

ADPFVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFS GKLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.