ProSpec,CD86 Human,CD86 人重组PRO-2620

  • CD86 Human

  • CD86 Human Recombinant
  • PRO-2620

Catalogue number

PRO-2620

Synonyms

B7-2/CD86, CD86, B7-2, B7.2, B70, CD28LG2, LAB72, T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B7.2, FUN-1.

Introduction

CD86, also known as B7-2 or Cluster of Differentiation 86 is a protein necessary for T cell activation and survival, it is expressed on cells that are antigen-presenting cells and acts as costimulatory signals for T cells. CD86 is the ligand for CD28  and CTLA-4 , two different proteins.

CD86,也称为 B7-2 或分化簇 86 是 T 细胞活化和存活所必需的蛋白质,它在抗原呈递细胞的细胞上表达,并作为 T 细胞的共刺激信号。 CD86 是 CD28 和 CTLA-4 这两种不同蛋白质的配体。

Description

CD86 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 223 amino acids and having a molecular mass of 25.6kDa . CD86 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 CD86 Human Recombinant 是单条糖基化多肽链,包含 223 个氨基酸,分子量为 25.6kDa。 CD86 在 C 末端以 6 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

CD86 protein solution contains Phosphate Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 90% as determined by -PAGE.

Amino acid sequence

YFNETADLPC QFANSQNQSL SELVVFWQDQ ENLVLNEVYL GKEKFDSVHS KYMGRTSFDS DSWTLRLHNL QIKDKGLYQC IIHHKKPTGM IRIHQMNSEL SVLANFSQPE IVPISNITEN VYINLTCSSI HGYPEPKKMS VLLRTKNSTI EYDGIMQKSQ DNVTELYDVS ISLSVSFPDV TSNMTIFCIL ETDKTRLLSS PFSIELEDPQ PPPDHIPHHH HHH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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