ProSpec,CRTAM Human,细胞毒性和调节性 T 细胞分子人重组PRO-2247

  • CRTAM Human

  • Cytotoxic and Regulatory T Cell Molecule Human Recombinant
  • PRO-2247

Catalogue number

PRO-2247

Synonyms

Cytotoxic and Regulatory T Cell Molecule, Class I MHC Restricted T Cell Associated Molecule, Class-I MHC-Restricted T-Cell-Associated Molecule, Class-I MHC-Restricted T Cell Associated Molecule, Cytotoxic and Regulatory T-Cell Molecule, CD355 Antigen, CD355.

Introduction

Cytotoxic and Regulatory T Cell Molecule, also known as CRTAM belongs to the immunoglobulin superfamily which complies with the structural characteristics of the JAM family and is phylogenetically more closely related to nectin-like proteins. CRTAM is implicated in epithelial cell adhesion. Furthermore, CRTAM interacts with CADM1 as well as promotes natural killer cell cytotoxicity.

细胞毒性和调节性 T 细胞分子,也称为 CRTAM,属于免疫球蛋白超家族,符合 JAM 家族的结构特征,在系统发育上与 nectin 样蛋白关系更密切。 CRTAM 与上皮细胞粘附有关。 此外,CRTAM 与 CADM1 相互作用并促进自然杀伤细胞的细胞毒性。

Description

CRTAM produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 278 amino acids and having a molecular mass of 31.0kDa. .
CRTAM is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 昆虫细胞中产生的 CRTAM 是单条糖基化多肽链,含有 278 个氨基酸,分子量为 31.0kDa。 .
CRTAM 在 C 末端用 8 个氨基酸 His 标签表达,并通过专有色谱技术进行纯化。

Source

Sf9, Insect cells.

Physical Appearance

Sterile filtered colorless solution.

Formulation

CRTAM protein solution contains phosphate buffered saline and 10% glycerol.

 

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYVST KEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCI IRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKSG LEHHHHHH.

Usage

ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.