ProSpec,IGLL1 Human,免疫球蛋白 λ 样多肽 1 人重组PRO-1390

    • IGLL1 Human

    • Immunoglobulin Lambda-Like Polypeptide 1 Human Recombinant
    • PRO-1390

Catalogue number

PRO-1390

Synonyms

14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, Immunoglobulin lambda-like polypeptide 1, CD179 antigen-like family member B, Ig lambda-5, Immunoglobulin omega polypeptide, Immunoglobulin-related protein 14.1, IGLL1.

Introduction

Immunoglobulin Lambda-Like Polypeptide 1 is one of the substitute light chain subunits and is a part of the immunoglobulin gene superfamily which does not undergo rearrangement. Two transcript variants encoding diverse isoforms have been found for IGLL1. Mutations in IGLL1 can bring about B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.
免疫球蛋白λ样多肽1是一种替代轻链亚基,是免疫球蛋白基因超家族的一部分,不发生重排。 已经为 IGLL1 发现了编码不同同种型的两种转录变体。 IGLL1 的突变可导致 B 细胞缺乏和无丙种球蛋白血症,这是一种常染色体隐性遗传病,其中很少或不产生丙种球蛋白或抗体。

Description

IGLL1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids and having a molecular mass of 21.5kDa. IGLL1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 IGLL1 Human Recombinant 是一条单一的、非糖基化的多肽链,含有 199 个氨基酸,分子量为 21.5kDa。 IGLL1 在 N 端与 23 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。

Source

E.coli.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

IGLL1 protein solution containing 20mM Tris-HCl buffer , 0.4M urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .

Avoid multiple freeze-thaw cycles.

Purity

Greater than 85% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSLLRPTAA SQSRALGPGA PGGSSRSSLR SRWGRFLLQR GSWTGPRCWP RGFQSKHNSV THVFGSGTQL TVLSQPKATP SVTLFPPSSE ELQANKATLV CLMNDFYPGI LTVTWKADGT PITQGVEMTT PSKQSNNKYA ASSYLSLTPE QWRSRRSYSC QVMHEGSTVE KTVAPAECS.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.