ProSpec CHM-007,BRAK Mouse,BRAK 小鼠重组,CHM-007

  • BRAK Mouse

  • BRAK Mouse Recombinant
  • CHM-007

Catalogue number

CHM-007

Synonyms

C-X-C motif chemokine 14, B-cell and monocyte-activating chemokine, Chemokine BRAK, Kidney-expressed chemokine CXC, MIP-2G, Small-inducible cytokine B14, Cxcl14, Bmac, Kec, Ks1, Mip2g, Scyb14, BRAK, NJAC, AI414372, bolekine, MIP2gamma, 1110031L23Rik, 1200006I23Rik.

Introduction

CXCL14 参与免疫调节和炎症过程。 BRAK 蛋白在结构上与细胞因子的 CXC 亚家族相关。 CXCL14 对单核细胞显示趋化活性,但对淋巴细胞、树突细胞、中性粒细胞或巨噬细胞没有趋化活性。 CXCL14 参与单核细胞衍生巨噬细胞的稳态。

Description

在大肠杆菌中产生的 CXCL14 Mouse Recombinant 是一种单一的、非糖基化的多肽链,含有 77 个氨基酸,分子量为 9.4kDa。
CXCL14 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

CXCL14 was lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4 and 500mM NaCl.

Solubility

It is recommended to reconstitute the lyophilized CXCL14 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized CXCL14 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL14 should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

Amino acid sequence

SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIVTTKS MSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE.

Biological Activity

The ED50 of CXCL14 as determined by its ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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